Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762

MYC addiction: a potential therapeutic target in MM

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BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

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Bromodomain and Extra-terminal (BET) Bromodomain Inhibition Activate Transcription via Transient Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein

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Targeting Epigenetic Readers in Cancer

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Place your BETs: the therapeutic potential of bromodomains

(2012) R.K. Prinjha et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

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(2011) Kenneth C. Anderson et al.   Annual Review of Pathology-Mechanisms of Disease

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma

(2011) W-J Chng et al.   LEUKEMIA

Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study

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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

(2011) Mark A. Dawson et al.   NATURE

Targeting MYC dependence in cancer by inhibiting BET bromodomains

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The genetic network controlling plasma cell differentiation

(2011) Stephen L. Nutt et al.   SEMINARS IN IMMUNOLOGY

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(2010) Christopher Alexander French   CANCER GENETICS AND CYTOGENETICS

c-Myc Regulates Transcriptional Pause Release

(2010) Peter B. Rahl et al.   CELL

Suppression of inflammation by a synthetic histone mimic

(2010) Edwige Nicodeme et al.   NATURE

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor

(2010) Gaelle Diribarne et al.   RNA Biology

Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells

(2009) Sungyoo Cho et al.   EMBO JOURNAL

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review

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Genome-Wide Transcriptional Response to 5-Aza-2'-Deoxycytidine and Trichostatin A in Multiple Myeloma Cells

(2008) G. Heller et al.   CANCER RESEARCH

The multi-tasking P-TEFb complex

(2008) Vanessa Brès et al.   CURRENT OPINION IN CELL BIOLOGY

IRF4 addiction in multiple myeloma

(2008) Arthur L. Shaffer et al.   NATURE