Regulation of platelet plug formation by phosphoinositide metabolism

Platelets lacking PIP5KI  have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion

(2013) Y. Wang et al.   BLOOD

Arterial thrombosis—insidious, unpredictable and deadly

(2011) Shaun P Jackson   NATURE MEDICINE

The novel platelet activation receptor CLEC-2

(2011) Katsue Suzuki-Inoue et al.   PLATELETS

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis

(2009) L. Lian et al.   BLOOD

Genetic evidence for a predominant role of PI3K  catalytic activity in ITAM- and integrin-mediated signaling in platelets

(2009) I. Canobbio et al.   BLOOD

Non-redundant Roles of Phosphoinositide 3-Kinase Isoforms α and β in Glycoprotein VI-induced Platelet Signaling and Thrombus Formation

(2009) Karen Gilio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase C 2 is necessary for separation of blood and lymphatic vasculature in mice

(2008) H. Ichise et al.   DEVELOPMENT

Membrane recognition by phospholipid-binding domains

(2008) Mark A. Lemmon   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of PIP5KI  demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation

(2008) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The p110  isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110 

(2008) J. Guillermet-Guibert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA