Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

A critical role for the retinoic acid signaling pathway in the pathophysiology of gastrointestinal graft-versus-host disease

(2013) X. Chen et al.   BLOOD

Promoting regulation via the inhibition of DNAM-1 after transplantation

(2013) M. Koyama et al.   BLOOD

A Retinoic Acid--Rich Tumor Microenvironment Provides Clonal Survival Cues for Tumor-Specific CD8+ T Cells

(2012) Y. Guo et al.   CANCER RESEARCH

Retinoic acid alleviates Con A-induced hepatitis and differentially regulates effector production in NKT cells

(2012) Kyoo-A Lee et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Shift of Graft-Versus-Host-Disease Target Organ Tropism by Dietary Vitamin A

(2012) Christian Koenecke et al.   PLoS One

Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17

(2011) H. Nishimori et al.   BLOOD

Instability of Foxp3 Expression Limits the Ability of Induced Regulatory T Cells to Mitigate Graft versus Host Disease

(2011) A. Beres et al.   CLINICAL CANCER RESEARCH

Essential Role for Retinoic Acid in the Promotion of CD4+ T Cell Effector Responses via Retinoic Acid Receptor Alpha

(2011) Jason A. Hall et al.   IMMUNITY

The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells

(2011) Shuichiro Takashima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A retinoic acid–dependent checkpoint in the development of CD4+T cell–mediated immunity

(2011) Karina Pino-Lagos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of Retinaldehyde Dehydrogenase Enzymes in Mucosal Dendritic Cells and Gut-Draining Lymph Node Stromal Cells Is Controlled by Dietary Vitamin A

(2011) R. Molenaar et al.   JOURNAL OF IMMUNOLOGY

Skin-draining lymph nodes contain dermis-derived CD103- dendritic cells that constitutively produce retinoic acid and induce Foxp3+ regulatory T cells

(2010) M. Guilliams et al.   BLOOD

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

(2010) S. L. Highfill et al.   BLOOD

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

(2009) L. K. Jasperson et al.   BLOOD

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

(2009) C. Bucher et al.   BLOOD

Acute graft-versus-host disease: from the bench to the bedside

(2009) G. Socie et al.   BLOOD

Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease

(2009) X. Chen et al.   BLOOD

Expression of the dominant negative retinoid receptor, RAR403, alters telencephalic progenitor proliferation, survival, and cell fate specification

(2008) Fatemeh Rajaii et al.   DEVELOPMENTAL BIOLOGY

Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo

(2008) Swantje I. Hammerschmidt et al.   JOURNAL OF EXPERIMENTAL MEDICINE