miR-21 mediates hematopoietic suppression in MDS by activating TGF-  signaling

Identification of a risk dependent microRNA expression signature in myelodysplastic syndromes

(2011) Lubomir Sokol et al.   BRITISH JOURNAL OF HAEMATOLOGY

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Reduced SMAD7 Leads to Overactivation of TGF-  Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-  Receptor I Kinase

(2010) L. Zhou et al.   CANCER RESEARCH

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

(2010) A Pellagatti et al.   LEUKEMIA

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Inhibition of the TGF-  receptor I kinase promotes hematopoiesis in MDS

(2008) L. Zhou et al.   BLOOD

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

(2008) Albert Tenesa et al.   NATURE GENETICS