The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model

Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia

(2011) A. C. Russ et al.   HAEMATOLOGICA

Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications

(2011) Guido Marcucci et al.   JOURNAL OF CLINICAL ONCOLOGY

Current findings for recurring mutations in acute myeloid leukemia

(2011) Shinichiro Takahashi   Journal of Hematology & Oncology

Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice

(2011) George S Vassiliou et al.   NATURE GENETICS

CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice

(2010) M. P. Martelli et al.   BLOOD

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

(2010) B. Falini et al.   BLOOD

Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1)

(2010) B. Falini et al.   BLOOD

Mutant nucleophosmin deregulates cell death and myeloid differentiation through excessive caspase-6 and -8 inhibition

(2010) S. M. Leong et al.   BLOOD

Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish

(2010) N. Bolli et al.   BLOOD

MicroRNA expression in maturing murine megakaryocytes

(2010) J. B. Opalinska et al.   BLOOD

Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives

(2010) Brunangelo Falini et al.   CURRENT OPINION IN ONCOLOGY

Export of microRNAs and microRNA-protective protein by mammalian cells

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model

(2009) K. Cheng et al.   BLOOD

AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features

(2009) C. Haferlach et al.   BLOOD

Favorable Prognostic Impact ofNPM1Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study

(2009) Heiko Becker et al.   JOURNAL OF CLINICAL ONCOLOGY

Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications

(2009) B Falini et al.   LEUKEMIA

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia

(2008) M. Jongen-Lavrencic et al.   BLOOD

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

(2008) R. G.W. Verhaak et al.   HAEMATOLOGICA

Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7γ

(2008) Paola Bonetti et al.   JOURNAL OF CELL BIOLOGY

A dose-dependent tug of war involving the NPM1 leukaemic mutant, nucleophosmin and ARF

(2008) N Bolli et al.   LEUKEMIA

A western blot assay for detecting mutant nucleophosmin (NPM1) proteins in acute myeloid leukaemia

(2008) M P Martelli et al.   LEUKEMIA

Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia

(2008) Richard F. Schlenk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

(2008) R. Garzon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA