Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome

Genome-wide high resolution DNA profiling of hairy cell leukaemia

(2013) Andrea Rinaldi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Pathogenesis of Human B Cell Lymphomas

(2012) Arthur L. Shaffer et al.   Annual Review of Immunology

High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

(2012) J. Edelmann et al.   BLOOD

Molecular distinctions between pediatric and adult mature B-cell non-Hodgkin lymphomas identified through genomic profiling

(2012) K. E. Deffenbacher et al.   BLOOD

Integrative Analysis Reveals an Outcome-Associated and Targetable Pattern of p53 and Cell Cycle Deregulation in Diffuse Large B Cell Lymphoma

(2012) Stefano Monti et al.   CANCER CELL

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Several mechanisms lead to the inactivation of the CDKN2A (P16), P14ARF, or CDKN2B (P15) genes in the GCB and ABC molecular DLBCL subtypes

(2012) Suzan Guney et al.   GENES CHROMOSOMES & CANCER

Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: a report from the International DLBCL Rituximab-CHOP Consortium Program Study

(2012) C Visco et al.   LEUKEMIA

Clinical and molecular characterization of diffuse large B-cell lymphomas with 13q14.3 deletion

(2011) M. Mian et al.   ANNALS OF ONCOLOGY

Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines

(2011) M. Lia et al.   BLOOD

NOTCH1 mutations in CLL associated with trisomy 12

(2011) V. Balatti et al.   BLOOD

The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation

(2011) D. Rossi et al.   BLOOD

Genome-wide DNA profiling better defines the prognosis of chronic lymphocytic leukaemia

(2011) Andrea Rinaldi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Absence of NOTCH1 gene mutations in MALT lymphomas

(2011) Afua Adjeiwaa Mensah et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Prognostic Significance of Various 13q14 Deletions in Chronic Lymphocytic Leukemia

(2011) P. Ouillette et al.   CLINICAL CANCER RESEARCH

NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL

(2011) I. Del Giudice et al.   HAEMATOLOGICA

Del(13q14.3) length matters: an integrated analysis of genomic, fluorescence in situ hybridization and clinical data in 169 chronic lymphocytic leukaemia patients with 13q deletion alone or a normal karyotype

(2011) Michael Mian et al.   HEMATOLOGICAL ONCOLOGY

Analysis of the chronic lymphocytic leukemia coding genome: role ofNOTCH1mutational activation

(2011) Giulia Fabbri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation

(2011) E Rao et al.   LEUKEMIA

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

Analysis of the coding genome of diffuse large B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE GENETICS

SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

(2011) Lili Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

(2011) Craig H Mermel et al.   GENOME BIOLOGY

Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome

(2010) A. Rinaldi et al.   BLOOD

Diffuse large B-cell lymphomas with CDKN2A deletion have a distinct gene expression signature and a poor prognosis under R-CHOP treatment: a GELA study

(2010) F. Jardin et al.   BLOOD

Single nucleotide polymorphism-arrays provide new insights in the pathogenesis of post-transplant diffuse large B-cell lymphoma

(2010) Andrea Rinaldi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Genomic lesions associated with a different clinical outcome in diffuse large B-Cell lymphoma treated with R-CHOP-21

(2010) Marta Scandurra et al.   BRITISH JOURNAL OF HAEMATOLOGY

Advances in the understanding of MYC-induced lymphomagenesis

(2010) Kay Klapproth et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cooperative Epigenetic Modulation by Cancer Amplicon Genes

(2010) Lixin Rui et al.   CANCER CELL

Integrative Genomics Analyses Reveal Molecularly Distinct Subgroups of B-Cell Chronic Lymphocytic Leukemia Patients with 13q14 Deletion

(2010) L. Mosca et al.   CLINICAL CANCER RESEARCH

New drugs for aggressive B-cell and T-cell lymphomas

(2010) Niels Murawski et al.   LANCET ONCOLOGY

13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia

(2010) H Parker et al.   LEUKEMIA

Genome wide DNA-profiling of HIV-related B-cell lymphomas

(2009) Daniela Capello et al.   BRITISH JOURNAL OF HAEMATOLOGY

Stereotyped B-Cell Receptor Is an Independent Risk Factor of Chronic Lymphocytic Leukemia Transformation to Richter Syndrome

(2009) D. Rossi et al.   CLINICAL CANCER RESEARCH

Genomic profiling of Richter's syndrome: recurrent lesions and differences with de novo diffuse large B-cell lymphomas

(2009) Marta Scandurra et al.   HEMATOLOGICAL ONCOLOGY

Richter syndrome: molecular insights and clinical perspectives

(2009) Davide Rossi et al.   HEMATOLOGICAL ONCOLOGY

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

(2008) G. Lenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA