Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function

The IGHV1-69/IGHJ3 recombinations of unmutated CLL are distinct from those of normal B cells

(2012) F. Forconi et al.   BLOOD

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

(2012) D. Rossi et al.   BLOOD

Association between B-cell receptor responsiveness and disease progression in B-cell chronic lymphocytic leukemia: results from single cell network profiling studies

(2012) A. Cesano et al.   HAEMATOLOGICA

Cellular origin and pathophysiology of chronic lymphocytic leukemia

(2012) Marc Seifert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells

(2011) S. Krysov et al.   BLOOD

B-cell receptor signaling in chronic lymphocytic leukemia

(2011) F. K. Stevenson et al.   BLOOD

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(2011) Carlo Calissano et al.   MOLECULAR MEDICINE

Inhibiting B-Cell Receptor Signaling Pathways in Chronic Lymphocytic Leukemia

(2011) Jan A. Burger   Current Hematologic Malignancy Reports

The lymph node microenvironment promotes B-cell receptor signaling, NF- B activation, and tumor proliferation in chronic lymphocytic leukemia

(2010) Y. Herishanu et al.   BLOOD

Impact of the host genetic background on prognosis of chronic lymphocytic leukemia

(2010) S. Rasi et al.   BLOOD

Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities

(2010) N. Chiorazzi et al.   BLOOD

BCR-Mediated Decrease of CXCR4 and CD62L in CLL – Letter

(2010) Maite P. Quiroga et al.   CANCER RESEARCH

Molecular underpinning of B-cell anergy

(2010) Yuval Yarkoni et al.   IMMUNOLOGICAL REVIEWS

CD49d is an independent prognostic marker that is associated with CXCR4 expression in CLL

(2010) Aneela Majid et al.   LEUKEMIA RESEARCH

Antigens in chronic lymphocytic leukemia—Implications for cell origin and leukemogenesis

(2010) Anders Rosén et al.   SEMINARS IN CANCER BIOLOGY

Chemokines and chemokine receptors in chronic lymphocytic leukemia (CLL): From understanding the basics towards therapeutic targeting

(2010) Jan A. Burger   SEMINARS IN CANCER BIOLOGY

The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL

(2009) F. Forconi et al.   BLOOD

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia

(2009) C. Calissano et al.   BLOOD

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406

(2009) M. P. Quiroga et al.   BLOOD

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

(2009) J. A. Burger et al.   BLOOD

The prognosis of clinical monoclonal B cell lymphocytosis differs from prognosis of Rai 0 chronic lymphocytic leukaemia and is recapitulated by biological risk factors

(2009) Davide Rossi et al.   BRITISH JOURNAL OF HAEMATOLOGY

Down-regulation of CXCR4 and CD62L in Chronic Lymphocytic Leukemia Cells Is Triggered by B-Cell Receptor Ligation and Associated with Progressive Disease

(2009) A. Vlad et al.   CANCER RESEARCH

Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors

(2008) J. Andrew Duty et al.   JOURNAL OF EXPERIMENTAL MEDICINE