SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G

Identification of SERPINB1 As a Physiological Inhibitor of Human Granzyme H

(2012) L. Wang et al.   JOURNAL OF IMMUNOLOGY

Educational paper

(2011) J. Merlijn van den Berg et al.   EUROPEAN JOURNAL OF PEDIATRICS

c-Cbl Ubiquitin Ligase Regulates Focal Adhesion Protein Turnover and Myofibril Degeneration Induced by Neutrophil Protease Cathepsin G

(2011) Khadija Rafiq et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical Role of SerpinB1 in Regulating Inflammatory Responses in Pulmonary Influenza Infection

(2011) Dapeng Gong et al.   JOURNAL OF INFECTIOUS DISEASES

SerpinB1 protects the mature neutrophil reserve in the bone marrow

(2011) C. Benarafa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophils, from Marrow to Microbes

(2010) Niels Borregaard   IMMUNITY

Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases

(2010) B. Korkmaz et al.   PHARMACOLOGICAL REVIEWS

Lysosomes as “Suicide Bags” in Cell Death: Myth or Reality?

(2009) Boris Turk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells

(2009) Michael Reich et al.   MOLECULAR IMMUNOLOGY

Death by a Thousand Cuts: Granzyme Pathways of Programmed Cell Death

(2008) Dipanjan Chowdhury et al.   Annual Review of Immunology

Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-3

(2008) B. J. van Raam et al.   BLOOD

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

(2008) Sébastien Conus et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constitutive neutrophil apoptosis: Mechanisms and regulation

(2007) Hongbo R. Luo et al.   AMERICAN JOURNAL OF HEMATOLOGY

Novel Mode for Neutrophil Protease Cathepsin G–Mediated Signaling

(2007) Khadija Rafiq et al.   CIRCULATION RESEARCH