Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors

Regulatory Effects of Programmed Cell Death 4 (PDCD4) Protein in Interferon (IFN)-Stimulated Gene Expression and Generation of Type I IFN Responses

(2012) B. Kroczynska et al.   MOLECULAR AND CELLULAR BIOLOGY

Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases

(2011) B. W. Konicek et al.   CANCER RESEARCH

Cap in hand: Targeting eIF4E

(2011) Peter M. Fischer   CELL CYCLE

Dual mTORC2/mTORC1 Targeting Results in Potent Suppressive Effects on Acute Myeloid Leukemia (AML) Progenitors

(2011) J. K. Altman et al.   CLINICAL CANCER RESEARCH

A Phase 1 Dose Escalation, Pharmacokinetic, and Pharmacodynamic Evaluation of eIF-4E Antisense Oligonucleotide LY2275796 in Patients with Advanced Cancer

(2011) D. S. Hong et al.   CLINICAL CANCER RESEARCH

Emerging roles for mammalian target of rapamycin inhibitors in the treatment of solid tumors and hematological malignancies

(2011) Nushmia Z. Khokhar et al.   CURRENT OPINION IN ONCOLOGY

Essential Role for Mnk Kinases in Type II Interferon (IFNγ) Signaling and Its Suppressive Effects on Normal Hematopoiesis

(2010) Sonali Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

(2010) Katherine L. B. Borden et al.   LEUKEMIA & LYMPHOMA

Negative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic Responses

(2010) J. K. Altman et al.   MOLECULAR PHARMACOLOGY

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development

(2010) T. Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin

(2009) S. Assouline et al.   BLOOD

Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia

(2009) Alberto M Martelli et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)- and Ribosomal Protein S6K-Mediated Signals

(2009) B. Kroczynska et al.   MOLECULAR AND CELLULAR BIOLOGY

Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses

(2009) S. Joshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Statin-Dependent Suppression of the Akt/Mammalian Target of Rapamycin Signaling Cascade and Programmed Cell Death 4 Up-Regulation in Renal Cell Carcinoma

(2008) J. Woodard et al.   CLINICAL CANCER RESEARCH

The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases)

(2008) Maria Buxade   Frontiers in Bioscience-Landmark

Regulation of Arsenic Trioxide-induced Cellular Responses by Mnk1 and Mnk2

(2008) Blazej Dolniak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY