The calcineurin-NFAT pathway negatively regulates megakaryopoiesis

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome

(2012) Sébastien Malinge et al.   JOURNAL OF CLINICAL INVESTIGATION

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

Regulation of fas/fas ligand-mediated apoptosis by nuclear factor of activated T cells in megakaryocytes

(2011) Laleh S. Arabanian et al.   BRITISH JOURNAL OF HAEMATOLOGY

Survivin localization during endomitosis of high ploidy mouse megakaryocytes

(2010) D. J. McCrann et al.   BLOOD

Peripheral blood cell counts in infants with Down's syndrome

(2010) S. M. Kivivuori et al.   CLINICAL GENETICS

Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome

(2010) Louise E. Reynolds et al.   NATURE

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

(2009) Kwan-Hyuck Baek et al.   NATURE

Nuclear factor of activated T cells (NFAT) mediates CD154 expression in megakaryocytes

(2008) S. A. Crist et al.   BLOOD

Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations

(2008) O. Tunstall-Pedoe et al.   BLOOD

Trisomy 21 enhances human fetal erythro-megakaryocytic development

(2008) S. T. Chou et al.   BLOOD

Regulation of Down Syndrome Critical Region 1 expression by Nuclear Factor of Activated T cells in megakaryocytes

(2008) Satu Kyttälä et al.   BRITISH JOURNAL OF HAEMATOLOGY

NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells

(2008) Valerie Horsley et al.   CELL

Selective role of calcineurin in haematopoiesis and lymphopoiesis

(2008) Elena M Gallo et al.   EMBO REPORTS

Extreme thrombocytosis associated with transient myeloproliferative disorder with Down Syndrome with t(11;17)(q13;q21)

(2006) Eun-Sil Park et al.   PEDIATRIC BLOOD & CANCER