A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenstrom macroglobulinemia
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Title
A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenstrom macroglobulinemia
Authors
Keywords
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Journal
BLOOD
Volume 122, Issue 7, Pages 1222-1232
Publisher
American Society of Hematology
Online
2013-07-09
DOI
10.1182/blood-2012-12-475111
References
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Related references
Note: Only part of the references are listed.- Prevalence and clinical significance of the MYD88 (L265P) somatic mutation in Waldenstrom's macroglobulinemia and related lymphoid neoplasms
- (2013) M. Varettoni et al. BLOOD
- MYD88 L265P in Waldenstrom macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction
- (2013) L. Xu et al. BLOOD
- Improved accuracy of discrimination between IgM Multiple Myeloma and Waldenström Macroglobulinaemia by testing forMYD88L265P mutations
- (2013) Wolfgang Willenbacher et al. BRITISH JOURNAL OF HAEMATOLOGY
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- (2012) Y.-T. Tai et al. BLOOD
- Bruton Tyrosine Kinase Inhibitor Ibrutinib (PCI-32765) Has Significant Activity in Patients With Relapsed/Refractory B-Cell Malignancies
- (2012) Ranjana H. Advani et al. JOURNAL OF CLINICAL ONCOLOGY
- IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas
- (2012) N Gachard et al. LEUKEMIA
- MYD88 L265P Somatic Mutation in IgM MGUS
- (2012) NEW ENGLAND JOURNAL OF MEDICINE
- MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia
- (2012) Steven P. Treon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activating L265P mutations of the MYD88 gene are common in primary central nervous system lymphoma
- (2011) Manuel Montesinos-Rongen et al. ACTA NEUROPATHOLOGICA
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Analysis of the coding genome of diffuse large B-cell lymphoma
- (2011) Laura Pasqualucci et al. NATURE GENETICS
- Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk
- (2011) Xingguang Liu et al. NATURE IMMUNOLOGY
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Oncogenically active MYD88 mutations in human lymphoma
- (2010) Vu N. Ngo et al. NATURE
- Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling
- (2010) Su-Chang Lin et al. NATURE
- Identification of Critical Residues of the MyD88 Death Domain Involved in the Recruitment of Downstream Kinases
- (2009) Maria Loiarro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting NF- B in Waldenstrom macroglobulinemia
- (2008) X. Leleu et al. BLOOD
- Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL-1 Receptor-Associated Kinase 1 To Facilitate NEMO Binding and the Activation of I B Kinase
- (2008) M. Windheim et al. MOLECULAR AND CELLULAR BIOLOGY
- Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2
- (2008) Tatsukata Kawagoe et al. NATURE IMMUNOLOGY
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