Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression

Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt- -catenin signaling

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A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin- 4 expression

(2012) S. Khurana et al.   BLOOD

Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia

(2012) Bin Zhang et al.   CANCER CELL

Hematopoietic Colony Formation from Human Growth Factor-Dependent TF1 Cells and Human Cord Blood Myeloid Progenitor Cells Depends on SHP2 Phosphatase Function

(2012) Hal E. Broxmeyer et al.   STEM CELLS AND DEVELOPMENT

Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival

(2011) A. Hamilton et al.   BLOOD

Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment

(2011) S. Chu et al.   BLOOD

Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS)

(2010) T. P. Hughes et al.   BLOOD

Deregulation of TWIST-1 in the CD34+ compartment represents a novel prognostic factor in chronic myeloid leukemia

(2010) E. Cosset et al.   BLOOD

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

(2010) Amie S. Corbin et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

(2010) Kazuhito Naka et al.   NATURE

Cancer Stem Cells: The Emerging Challenge of Drug Targeting

(2009) Roger Besancon et al.   CURRENT MEDICINAL CHEMISTRY

Effects of imatinib mesylate in osteoblastogenesis

(2009) Daniele Tibullo et al.   EXPERIMENTAL HEMATOLOGY

Bone Morphogenetic Proteins Are Overexpressed in the Bone Marrow of Primary Myelofibrosis and Are Apparently Induced by Fibrogenic Cytokines

(2008) Oliver Bock et al.   AMERICAN JOURNAL OF PATHOLOGY

BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling

(2008) S. Jeanpierre et al.   BLOOD

Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Pathway Inhibits Differentiation of Glioblastoma-Initiating Cells

(2008) Jeongwu Lee et al.   CANCER CELL