Notch signals are required for in vitro but not in vivo maintenance of human hematopoietic stem cells and delay the appearance of multipotent progenitors
Published 2013 View Full Article
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Title
Notch signals are required for in vitro but not in vivo maintenance of human hematopoietic stem cells and delay the appearance of multipotent progenitors
Authors
Keywords
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Journal
BLOOD
Volume 123, Issue 8, Pages 1167-1177
Publisher
American Society of Hematology
Online
2013-12-21
DOI
10.1182/blood-2013-07-505099
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- Ex vivo expansion of human hematopoietic stem and progenitor cells
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- Notch signaling: simplicity in design, versatility in function
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- Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells
- (2010) Jason M. Butler et al. Cell Stem Cell
- Direct Comparison of Dll1- and Dll4-Mediated Notch Activation Levels Shows Differential Lymphomyeloid Lineage Commitment Outcomes
- (2010) M. Mohtashami et al. JOURNAL OF IMMUNOLOGY
- Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development
- (2010) Sergei Doulatov et al. NATURE IMMUNOLOGY
- Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution
- (2010) Colleen Delaney et al. NATURE MEDICINE
- Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells
- (2009) G. Awong et al. BLOOD
- Genome-wide Lineage-Specific Transcriptional Networks Underscore Ikaros-Dependent Lymphoid Priming in Hematopoietic Stem Cells
- (2009) Samuel Yao-Ming Ng et al. IMMUNITY
- In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood
- (2009) Christopher Y Park et al. Nature Protocols
- Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells
- (2008) Ivan Maillard et al. Cell Stem Cell
- Signaling pathways governing stem-cell fate
- (2007) U. Blank et al. BLOOD
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