IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia

IL-21 Stimulates Human Myeloma Cell Growth through an Autocrine IGF-1 Loop

(2014) E. Menoret et al.   JOURNAL OF IMMUNOLOGY

STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation

(2014) S. A. Diehl et al.   JOURNAL OF IMMUNOLOGY

IL-6 Triggers IL-21 production by human CD4+ T cells to drive STAT3-dependent plasma cell differentiation in B cells

(2012) Sean A Diehl et al.   IMMUNOLOGY AND CELL BIOLOGY

Establishment and characterization of a novel Waldenstrom macroglobulinemia cell line, MWCL-1

(2011) L. S. Hodge et al.   BLOOD

Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity

(2011) S. F. Elsawa et al.   BLOOD

IL-21 Contributes to JAK3/STAT3 Activation and Promotes Cell Growth in ALK-Positive Anaplastic Large Cell Lymphoma

(2009) Jennifer Dien Bard et al.   AMERICAN JOURNAL OF PATHOLOGY

Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas

(2009) K. A. Sarosiek et al.   BLOOD

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells

(2009) Oliver Dienz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Simple: A Sequential Immunoperoxidase Labeling and Erasing Method

(2009) George Glass et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis

(2008) F. A. Scheeren et al.   BLOOD

IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro

(2008) A. Gowda et al.   BLOOD

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

(2007) Rosanne Spolski et al.   Annual Review of Immunology