Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis

The withdrawal of Activated Protein C from the use in patients with severe sepsis and DIC [Amendment to the BCSH guideline on disseminated intravascular coagulation]

(2012) Jecko Thachil et al.   BRITISH JOURNAL OF HAEMATOLOGY

Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding

(2011) A. S. Revenko et al.   BLOOD

Protective Roles for Fibrin, Tissue Factor, Plasminogen Activator Inhibitor-1, and Thrombin Activatable Fibrinolysis Inhibitor, but Not Factor XI, during Defense against the Gram-Negative Bacterium Yersinia enterocolitica

(2011) D. Luo et al.   JOURNAL OF IMMUNOLOGY

Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes

(2011) Asako Itakura et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Thrombin Mutant W215A/E217A Treatment Improves Neurological Outcome and Reduces Cerebral Infarct Size in a Mouse Model of Ischemic Stroke

(2011) Michelle A. Berny-Lang et al.   STROKE

A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo

(2010) Q. Cheng et al.   BLOOD

Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk

(2010) H. Zhang et al.   BLOOD

Polyphosphate exerts differential effects on blood clotting, depending on polymer size

(2010) S. A. Smith et al.   BLOOD

Studies on Fletcher trait and Fitzgerald trait

(2010) Hidehiko Saito   THROMBOSIS AND HAEMOSTASIS

Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis

(2010) Ophira Salomon et al.   THROMBOSIS AND HAEMOSTASIS

Identification of Coagulation Factor XI as a Ligand for Platelet Apolipoprotein E Receptor 2 (ApoER2)

(2009) Tara C. White-Adams et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Factor XI contributes to thrombin generation in the absence of factor XII

(2009) D. V. Kravtsov et al.   BLOOD

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

(2008) E. I. Tucker et al.   BLOOD

Reduced incidence of ischemic stroke in patients with severe factor XI deficiency

(2008) O. Salomon et al.   BLOOD

Survival Advantage of Coagulation Factor XI–Deficient Mice during Peritoneal Sepsis

(2008) Erik I. Tucker et al.   JOURNAL OF INFECTIOUS DISEASES

Evolution of the contact phase of vertebrate blood coagulation

(2008) M. B. PONCZEK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS