Induction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activation

MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation

(2012) E. C. Smith et al.   BLOOD

Role of RhoA-Specific Guanine Exchange Factors in Regulation of Endomitosis in Megakaryocytes

(2012) Yuan Gao et al.   DEVELOPMENTAL CELL

Extracellular matrix structure and nano-mechanics determine megakaryocyte function

(2011) A. Malara et al.   BLOOD

Nuclear transport of the serum response factor coactivator MRTF-A is downregulated at tensional homeostasis

(2011) Karen M McGee et al.   EMBO REPORTS

Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance

(2011) Wanzhu Jin et al.   JOURNAL OF CLINICAL INVESTIGATION

Megakaryocyte-matrix interaction within bone marrow: new roles for fibronectin and factor XIII-A

(2010) A. Malara et al.   BLOOD

Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction

(2010) Eric M. Small et al.   CIRCULATION RESEARCH

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A

(2010) Rafał Pawłowski et al.   EMBO JOURNAL

The serum response factor (SRF)/megakaryocytic acute leukemia (MAL) network participates in megakaryocyte development

(2010) C Ragu et al.   LEUKEMIA

Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423

(2009) Chris R. Evelyn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Role for MKL1 in megakaryocytic maturation

(2009) E.-c. Cheng et al.   BLOOD

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

(2009) L. Gilles et al.   BLOOD

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

Negative Regulation of the EGFR-MAPK Cascade by Actin-MAL-Mediated Mig6/Errfi-1 Induction

(2009) Arnaud Descot et al.   MOLECULAR CELL

MicroRNA-Mediated Control of Cell Fate in Megakaryocyte-Erythrocyte Progenitors

(2008) Jun Lu et al.   DEVELOPMENTAL CELL

Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling

(2008) S. Busche et al.   JOURNAL OF CELL SCIENCE