p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes

Cellular Iron Depletion Stimulates the JNK and p38 MAPK Signaling Transduction Pathways, Dissociation of ASK1-Thioredoxin, and Activation of ASK1

(2011) Yu Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

(2011) Cornelis J.H. Pronk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype

(2011) Chantal Stoepker et al.   NATURE GENETICS

Mutations of the SLX4 gene in Fanconi anemia

(2011) Yonghwan Kim et al.   NATURE GENETICS

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Heat shock protein 70 together with its co-chaperone CHIP inhibits TNF-α induced apoptosis by promoting proteasomal degradation of apoptosis signal-regulating kinase1

(2010) Yanhong Gao et al.   APOPTOSIS

MAPKAP kinases MK2 and MK3 in inflammation: Complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin

(2010) Natalia Ronkina et al.   BIOCHEMICAL PHARMACOLOGY

Human FANCC is hypomorphic in murine Fancc-deficient cells

(2010) L. E. Hays et al.   BLOOD

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia

(2010) A. C. Pulliam-Leath et al.   BLOOD

TRIF Signaling Stimulates Translation of TNF-  mRNA via Prolonged Activation of MK2

(2010) P. Gais et al.   JOURNAL OF IMMUNOLOGY

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

NF-κB participates in chemokine receptor 7-mediated cell survival in metastatic squamous cell carcinoma of the head and neck

(2010) Sun   ONCOLOGY REPORTS

TLR8-dependent TNF-  overexpression in Fanconi anemia group C cells

(2009) S. M. Vanderwerf et al.   BLOOD

Distinct roles of stress-activated protein kinases in Fanconi anemia type C-deficient hematopoiesis

(2009) M. R. Saadatzadeh et al.   BLOOD

Dasatinib inhibits the secretion of TNF-α following TLR stimulation in vitro and in vivo

(2009) Cara K. Fraser et al.   EXPERIMENTAL HEMATOLOGY

The genetic and molecular basis of Fanconi anemia

(2008) Johan P. de Winter et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages

(2007) Maria J. Smolinska et al.   MOLECULAR IMMUNOLOGY