ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53

Class IA PI3Kinase Regulatory Subunit, p85α, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes

(2012) Subha Krishnan et al.   PLoS One

Transcription factor networks in erythroid cell and megakaryocyte development

(2011) L. C. Dore et al.   BLOOD

Rho Kinase Regulates the Survival and Transformation of Cells Bearing Oncogenic Forms of KIT, FLT3, and BCR-ABL

(2011) Raghuveer Singh Mali et al.   CANCER CELL

Stress erythropoiesis: new signals and new stress progenitor cells

(2011) Robert F Paulson et al.   CURRENT OPINION IN HEMATOLOGY

Balanced Interactions between Lyn, the p85  Regulatory Subunit of Class IA Phosphatidylinositol-3-Kinase, and SHIP Are Essential for Mast Cell Growth and Maturation

(2011) P. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Negative Autoregulation by Fas Stabilizes Adult Erythropoiesis and Accelerates Its Stress Response

(2011) Miroslav Koulnis et al.   PLoS One

The MAPK ERK1 is a negative regulator of the adult steady-state splenic erythropoiesis

(2010) S. Guihard et al.   BLOOD

Essential role for focal adhesion kinase in regulating stress hematopoiesis

(2010) S. Vemula et al.   BLOOD

Erythropoietin stimulates spleen BMP4-dependent stress erythropoiesis and partially corrects anemia in a mouse model of generalized inflammation

(2010) S. Millot et al.   BLOOD

Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling

(2010) A-S Gabet et al.   CELL DEATH AND DIFFERENTIATION

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen

(2010) T. A. Kalfa et al.   HAEMATOLOGICA

Rho GTPases in hematopoiesis and hemopathies

(2009) J. C. Mulloy et al.   BLOOD

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

(2009) S. Vemula et al.   BLOOD

ROCK inhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells

(2009) David A. Claassen et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Oxidative Stress in the Regulation of Normal and Neoplastic Hematopoiesis

(2008) Saghi Ghaffari   ANTIOXIDANTS & REDOX SIGNALING

Oxidative Stress in Fanconi Anemia Hematopoiesis and Disease Progression

(2008) Wei Du et al.   ANTIOXIDANTS & REDOX SIGNALING

Maintenance of the BMP4-dependent stress erythropoiesis pathway in the murine spleen requires hedgehog signaling

(2008) J. M. Perry et al.   BLOOD

Applications for ROCK kinase inhibition

(2008) Michael F Olson   CURRENT OPINION IN CELL BIOLOGY

ROS and p53: A versatile partnership

(2008) Bin Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2

(2008) Peng Ji et al.   NATURE CELL BIOLOGY

Identification of ROCK1 as an Upstream Activator of the JIP-3 to JNK Signaling Axis in Response to UVB Damage

(2008) P. P. Ongusaha et al.   Science Signaling