Low hepcidin accounts for the proinflammatory status associated with iron deficiency

Iron Homeostasis and the Inflammatory Response

(2010) Marianne Wessling-Resnick   Annual Review of Nutrition

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

(2010) B. J. Sasu et al.   BLOOD

Increased susceptibility to iron deficiency of Tmprss6-haploinsufficient mice

(2010) A. Nai et al.   BLOOD

Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project

(2010) A. Piperno et al.   BLOOD

Altered hepatic BMP signaling pathway in human HFE hemochromatosis

(2010) Giuliano Bolondi et al.   BLOOD CELLS MOLECULES AND DISEASES

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Hepcidin expression in anemia of chronic disease and concomitant iron-deficiency anemia

(2010) Pan-pan Cheng et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice

(2010) Ivana De Domenico et al.   JOURNAL OF CLINICAL INVESTIGATION

Alterations of systemic and muscle iron metabolism in human subjects treated with low-dose recombinant erythropoietin

(2009) P. Robach et al.   BLOOD

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression

(2009) L. Kautz et al.   BLOOD

Hepcidin targets ferroportin for degradation in hepatocytes

(2009) G. Ramey et al.   HAEMATOLOGICA

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

(2009) Daniel F. Wallace et al.   HEPATOLOGY

Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD

(2009) Guillem Casanovas et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

(2009) Delphine Meynard et al.   NATURE GENETICS

Iron availability and infection

(2008) Eugene D. Weinberg   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

(2008) A. R. Folgueras et al.   BLOOD

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

(2008) L. Kautz et al.   BLOOD

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE