Overactivation of plasmacytoid dendritic cells inhibits antiviral T-cell responses: a model for HIV immunopathogenesis

Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α–producing and partially matured phenotype

(2011) Meagan O’Brien et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence of dysregulation of dendritic cells in primary HIV infection

(2010) R. L. Sabado et al.   BLOOD

Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection

(2010) R. Cagliani et al.   HUMAN MOLECULAR GENETICS

Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of TH17 to Regulatory T Cells in HIV Disease

(2010) D. Favre et al.   Science Translational Medicine

Plasmacytoid dendritic cells express TRAIL and induce CD4+ T-cell apoptosis in HIV-1 viremic patients

(2009) G. Stary et al.   BLOOD

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

(2009) Béatrice Jacquelin et al.   JOURNAL OF CLINICAL INVESTIGATION

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

(2009) Steven E. Bosinger et al.   JOURNAL OF CLINICAL INVESTIGATION

Glycerol monolaurate prevents mucosal SIV transmission

(2009) Qingsheng Li et al.   NATURE

Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology

(2008) S. Baenziger et al.   BLOOD

PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: Restricted expression of type I interferon receptor by CCR5-expressing leukocytes

(2008) Adriano Boasso et al.   CLINICAL IMMUNOLOGY

The hunt for an HIV vaccine: time to rethink recent failures

(2008) Adriano Boasso et al.   LANCET

HIV-Induced Type I Interferon and Tryptophan Catabolism Drive T Cell Dysfunction Despite Phenotypic Activation

(2008) Adriano Boasso et al.   PLoS One

Chronic innate immune activation as a cause of HIV-1 immunopathogenesis

(2007) Adriano Boasso et al.   CLINICAL IMMUNOLOGY