A mutation in the human Uncoordinated 119 gene impairs TCR signaling and is associated with CD4 lymphopenia

Idiopathic CD4+ T lymphopenia without autoimmunity or granulomatous disease in the slipstream of RAG mutations

(2011) T. W. Kuijpers et al.   BLOOD

Second messenger role for Mg2+ revealed by human T-cell immunodeficiency

(2011) Feng-Yen Li et al.   NATURE

More than just SCID—The phenotypic range of combined immunodeficiencies associated with mutations in the recombinase activating genes (RAG) 1 and 2

(2010) Tim Niehues et al.   CLINICAL IMMUNOLOGY

Uncoordinated 119 Preferentially Induces Th2 Differentiation and Promotes the Development of Asthma

(2010) M. M. Gorska et al.   JOURNAL OF IMMUNOLOGY

Idiopathic CD4+ T-cell lymphocytopenia is associated with impaired membrane expression of the chemokine receptor CXCR4

(2009) D. Scott-Algara et al.   BLOOD

T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance

(2009) Robert J. Salmond et al.   IMMUNOLOGICAL REVIEWS

Uncoordinated 119 Protein Controls Trafficking of Lck via the Rab11 Endosome and Is Critical for Immunological Synapse Formation

(2009) M. M. Gorska et al.   JOURNAL OF IMMUNOLOGY

Unc119 Protects from Shigella Infection by Inhibiting the Abl Family Kinases

(2009) Ramarao Vepachedu et al.   PLoS One

Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors

(2008) D. I. Zonios et al.   BLOOD