NK314 potentiates antitumor activity with adult T-cell leukemia-lymphoma cells by inhibition of dual targets on topoisomerase II  and DNA-dependent protein kinase

Interleukin-2 receptor downstream events in regulatory T cells: Implications for the choice of immunosuppressive drug therapy

(2010) Robert Zeiser et al.   CELL CYCLE

HTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches

(2008) John M. Taylor et al.   APOPTOSIS

Acute leukemia as a secondary malignancy in children and adolescents: Current findings and issues

(2008) Nobuko Hijiya et al.   CANCER

KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation

(2008) Takuya Abe et al.   CELLULAR SIGNALLING

DNA-Dependent Protein Kinase Is a Therapeutic Target and an Indicator of Poor Prognosis in B-Cell Chronic Lymphocytic Leukemia

(2008) E. Willmore et al.   CLINICAL CANCER RESEARCH

DNA Damage Repair and Response Proteins as Targets for Cancer Therapy

(2008) Howard Lieberman   CURRENT MEDICINAL CHEMISTRY

DNA repair deficiency as a therapeutic target in cancer

(2008) Sarah A Martin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

DNA-damage repair; the good, the bad, and the ugly

(2008) Razqallah Hakem   EMBO JOURNAL

NK314, a Topoisomerase II Inhibitor That Specifically Targets the α Isoform

(2008) Eriko Toyoda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase

(2008) Sarah S. Durkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activities of DNA-PK and Ku86, but not Ku70, may predict sensitivity to cisplatin in human gliomas

(2008) Cui-Jie Shao et al.   JOURNAL OF NEURO-ONCOLOGY

The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

(2008) J. E. Deweese et al.   NUCLEIC ACIDS RESEARCH

NK314, a novel topoisomerase II inhibitor, induces rapid DNA double-strand breaks and exhibits superior antitumor effects against tumors resistant to other topoisomerase II inhibitors

(2007) Takeshi Onda et al.   CANCER LETTERS