FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma

CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP

(2010) W. Ju et al.   BLOOD

Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia

(2010) J. Pancewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models

(2009) M. G. Cornejo et al.   BLOOD

Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability

(2009) C. A. Pise-Masison et al.   BLOOD

FERM proteins in animal morphogenesis

(2009) Ulrich Tepass   CURRENT OPINION IN GENETICS & DEVELOPMENT

Janus kinases in immune cell signaling

(2009) Kamran Ghoreschi et al.   IMMUNOLOGICAL REVIEWS

Selectivity and therapeutic inhibition of kinases: to be or not to be?

(2009) Kamran Ghoreschi et al.   NATURE IMMUNOLOGY

JAK mutations in high-risk childhood acute lymphoblastic leukemia

(2009) C. G. Mullighan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism

(2008) J. Chen et al.   BLOOD

Down-regulation of TCF8 is involved in the leukemogenesis of adult T-cell leukemia/lymphoma

(2008) T. Hidaka et al.   BLOOD

Duffy (Fy),DARC, and neutropenia among women from the United States, Europe and the Caribbean

(2008) Victor R. Grann et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ligand-independent Homomeric and Heteromeric Complexes between Interleukin-2 or -9 Receptor Subunits and the γ Chain

(2008) Yaniv Malka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Biology of Interleukin-2

(2007) Thomas R. Malek   Annual Review of Immunology