The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs

Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells

(2011) Barbara Varnum-Finney et al.   JOURNAL OF CLINICAL INVESTIGATION

Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7  overexpression

(2010) H. Iriuchishima et al.   BLOOD

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

(2010) Hui-Kuan Lin et al.   NATURE

Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase–substrate complex

(2010) Linsey Reavie et al.   NATURE IMMUNOLOGY

Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis

(2009) S. Rodriguez et al.   BLOOD

Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease

(2008) A. Agarwal et al.   BLOOD

Hematopoietic Stem Cell Quiescence Is Maintained by Compound Contributions of the Retinoblastoma Gene Family

(2008) Patrick Viatour et al.   Cell Stem Cell

Tumor necrosis factor-α and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation

(2008) Luis Fernandez et al.   EXPERIMENTAL HEMATOLOGY

The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells

(2008) C. Rathinam et al.   GENES & DEVELOPMENT

Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7

(2008) Benjamin J. Thompson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

(2008) Keith W. Orford et al.   NATURE REVIEWS GENETICS