A novel role of IL-17-producing lymphocytes in mediating lytic bone disease in multiple myeloma

A Th17-like developmental process leads to CD8+Tc17 cells with reduced cytotoxic activity

(2009) Magdalena Huber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CTLA-4 directly inhibits osteoclast formation

(2008) R Axmann et al.   ANNALS OF THE RHEUMATIC DISEASES

High serum YKL-40 concentration is associated with severe bone disease in newly diagnosed multiple myeloma patients

(2008) Anne K. Mylin et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation

(2008) D. Atanackovic et al.   HAEMATOLOGICA

Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma

(2008) I Breitkreutz et al.   LEUKEMIA

IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells

(2008) T. Korn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE

RANK ligand as a therapeutic target for bone metastases and multiple myeloma

(2007) G. David Roodman et al.   CANCER TREATMENT REVIEWS