Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug

Induction of angiogenesis by normal and malignant plasma cells

(2009) D. Hose et al.   BLOOD

Increased signaling through p62 in the marrow microenvironment increases myeloma cell growth and osteoclast formation

(2009) Y. Hiruma et al.   BLOOD

Multiple myeloma

(2008) R. A. Kyle et al.   BLOOD

Potent and Highly Selective Hypoxia-Activated Achiral Phosphoramidate Mustards as Anticancer Drugs

(2008) Jian-Xin Duan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bone marrow microenvironment and the identification of new targets for myeloma therapy

(2008) K Podar et al.   LEUKEMIA

Lactate dehydrogenase 5 expression in non-Hodgkin B-cell lymphomas is associated with hypoxia regulated proteins

(2008) Alexandra Giatromanolaki et al.   LEUKEMIA & LYMPHOMA

Design of anticancer prodrugs for reductive activation

(2008) Yu Chen et al.   MEDICINAL RESEARCH REVIEWS