GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

A Phase III Study of Belatacept-based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

(2010) F. Vincenti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Haploidentical Bone Marrow Transplantation in Primary Immune Deficiency: Stem Cell Selection and Manipulation

(2010) David Hagin et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Stimulation of Naive CD8 + T Cells by a Variant Viral Epitope Induces Activation and Enhanced Apoptosis

(2010) Rebecca M. Ream et al.   JOURNAL OF IMMUNOLOGY

A Human Anti-CD40 Monoclonal Antibody, 4D11, for Kidney Transplantation in Cynomolgus Monkeys: Induction and Maintenance Therapy

(2009) T. Aoyagi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

(2009) T. Yi et al.   BLOOD

The clinical utility of inhibiting CD28-mediated costimulation

(2009) Peter S. Linsley et al.   IMMUNOLOGICAL REVIEWS

IL-7 and the HIV Tat protein act synergistically to down-regulate CD127 expression on CD8 T cells

(2009) E. Faller et al.   INTERNATIONAL IMMUNOLOGY

Anti-CD40 Monoclonal Antibody Synergizes with CTLA4-Ig in Promoting Long-Term Graft Survival in Murine Models of Transplantation

(2009) C. R. Gilson et al.   JOURNAL OF IMMUNOLOGY

IL-15 Regulates Both Quantitative and Qualitative Features of the Memory CD8 T Cell Pool

(2009) Michelle M. Sandau et al.   JOURNAL OF IMMUNOLOGY

Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function

(2009) Maciej Kmieciak et al.   Journal of Translational Medicine

Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates

(2009) Tim A Weaver et al.   NATURE MEDICINE

New Immunosuppressive Protocols With the Advent of Novel Biological Drugs

(2009) Josep M. Cruzado et al.   TRANSPLANTATION

Expanded Nonhuman Primate Tregs Exhibit a Unique Gene Expression Signature and Potently Downregulate Alloimmune Responses

(2008) A. Anderson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A biomarker panel for acute graft-versus-host disease

(2008) S. Paczesny et al.   BLOOD

Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies

(2008) J. K. Davies et al.   BLOOD

In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

(2008) M. J. Carlson et al.   BLOOD

CD28/CD154 Blockade Prevents Autoimmune Diabetes by Inducing Nondeletional Tolerance After Effector T-Cell Inhibition and Regulatory T-Cell Expansion

(2008) M. R. Rigby et al.   DIABETES

Costimulation blockade in autoimmunity and transplantation

(2008) Flavio Vincenti   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Down‐Regulation of Interleukin‐7 Receptor (CD127) in HIV Infection Is Associated with T Cell Activation and Is a Main Factor Influencing Restoration of CD4+Cells after Antiretroviral Therapy

(2008) José M. Benito et al.   JOURNAL OF INFECTIOUS DISEASES

The haploidentical option for high-risk haematological malignancies

(2007) Franco Aversa et al.   BLOOD CELLS MOLECULES AND DISEASES