8-Aminoadenosine inhibits Akt/mTOR and Erk signaling in mantle cell lymphoma

8-Amino-Adenosine Inhibits Multiple Mechanisms of Transcription

(2010) J. A. Frey et al.   MOLECULAR CANCER THERAPEUTICS

Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues

(2009) Lisa S. Chen et al.   BIOCHEMICAL PHARMACOLOGY

Preclinical activity of 8-chloroadenosine with mantle cell lymphoma: roles of energy depletion and inhibition of DNA and RNA synthesis

(2009) Jennifer B. Dennison et al.   BRITISH JOURNAL OF HAEMATOLOGY

Phosphatidylinositol 3'-Kinase Catalytic Subunit   Gene Amplification Contributes to the Pathogenesis of Mantle Cell Lymphoma

(2009) A. Psyrri et al.   CLINICAL CANCER RESEARCH

Targeting Glucose Consumption and Autophagy in Myeloma with the Novel Nucleoside Analogue 8-Aminoadenosine

(2009) Mala Shanmugam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase III Study to Evaluate Temsirolimus Compared With Investigator's Choice Therapy for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

(2009) Georg Hess et al.   JOURNAL OF CLINICAL ONCOLOGY

Mcl-1: the 1 in CLL

(2008) V. Gandhi et al.   BLOOD

Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma

(2008) J. Dal Col et al.   BLOOD

Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

(2008) L. Paoluzzi et al.   BLOOD

Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma

(2008) Stephen M. Ansell et al.   CANCER

A Phase 2 Clinical Trial of Deforolimus (AP23573, MK-8669), a Novel Mammalian Target of Rapamycin Inhibitor, in Patients with Relapsed or Refractory Hematologic Malignancies

(2008) D. A. Rizzieri et al.   CLINICAL CANCER RESEARCH

Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma

(2008) Victor Y. Yazbeck et al.   EXPERIMENTAL HEMATOLOGY

Specific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2

(2008) M Klier et al.   LEUKEMIA