Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells

βTrCP- and Rsk1/2-Mediated Degradation of BimEL Inhibits Apoptosis

(2009) Elinor Dehan et al.   MOLECULAR CELL

Activity of the BH3 mimetic ABT-737 on polycythemia vera erythroid precursor cells

(2008) A. Zeuner et al.   BLOOD

Myeloproliferative disorders

(2008) R. L. Levine et al.   BLOOD

Hsp90 Inhibition Suppresses Mutant EGFR-T790M Signaling and Overcomes Kinase Inhibitor Resistance

(2008) T. Shimamura et al.   CANCER RESEARCH

Erythropoietin-induced phosphorylation/degradation of BIM contributes to survival of erythroid cells

(2008) Randolph M. Abutin et al.   EXPERIMENTAL HEMATOLOGY

Effects of the JAK2 Inhibitor, AZ960, on Pim/BAD/BCL-xL Survival Signaling in the Human JAK2 V617F Cell Line SET-2

(2008) Joseph M. Gozgit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic

(2008) Mark S. Cragg et al.   JOURNAL OF CLINICAL INVESTIGATION

Mining for JAK–STAT mutations in cancer

(2008) Stefan N. Constantinescu et al.   TRENDS IN BIOCHEMICAL SCIENCES