Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM

Cellular responses to reactive oxygen species-induced DNA damage and aging

(2008) Catharina Bertram et al.   BIOLOGICAL CHEMISTRY

Bendamustine Is Effective in p53-Deficient B-Cell Neoplasms and Requires Oxidative Stress and Caspase-Independent Signaling

(2008) G. Roue et al.   CLINICAL CANCER RESEARCH

Fludarabine, Cyclophosphamide, and Mitoxantrone as Initial Therapy of Chronic Lymphocytic Leukemia: High Response Rate and Disease Eradication

(2008) F. Bosch et al.   CLINICAL CANCER RESEARCH

Bendamustine (Treanda) Displays a Distinct Pattern of Cytotoxicity and Unique Mechanistic Features Compared with Other Alkylating Agents

(2008) L. M. Leoni et al.   CLINICAL CANCER RESEARCH

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

(2008) Sugako Oka et al.   EMBO JOURNAL

Identification of a Conserved Rac-binding Site on NADPH Oxidases Supports a Direct GTPase Regulatory Mechanism

(2008) Yu-Ya Kao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase II Multicenter Study of Bendamustine Plus Rituximab in Patients With Relapsed Indolent B-Cell and Mantle Cell Non-Hodgkin's Lymphoma

(2008) K. Sue Robinson et al.   JOURNAL OF CLINICAL ONCOLOGY

Sequential Therapy With Fludarabine, High-Dose Cyclophosphamide, and Rituximab in Previously Untreated Patients With Chronic Lymphocytic Leukemia Produces High-Quality Responses: Molecular Remissions Predict for Durable Complete Responses

(2008) Nicole Lamanna et al.   JOURNAL OF CLINICAL ONCOLOGY

E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines

(2008) M Kitagawa et al.   ONCOGENE

Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis

(2007) Tomohiro Nakamura et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY