Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia

Mutations of polycomb-associated geneASXL1in myelodysplastic syndromes and chronic myelomonocytic leukaemia

(2009) Véronique Gelsi-Boyer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice

(2009) C.L. Fisher et al.   DEVELOPMENTAL BIOLOGY

A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling

(2009) Anne-Kathrin Classen et al.   NATURE GENETICS

Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling

(2009) Anne-Marie Martinez et al.   NATURE GENETICS

Mll5 contributes to hematopoietic stem cell fitness and homeostasis

(2008) Y. Zhang et al.   BLOOD

Loss of Mll5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation

(2008) M. Heuser et al.   BLOOD

Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog Mll5

(2008) V. Madan et al.   BLOOD

Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: Potential role in progression

(2008) Luigi Scotto et al.   GENES CHROMOSOMES & CANCER

Isolation and Characterization of a Novel H1.2 Complex That Acts as a Repressor of p53-mediated Transcription

(2008) Kyunghwan Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PHD fingers in human diseases: Disorders arising from misinterpreting epigenetic marks

(2008) Lindsey A. Baker et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer

(2008) Q. An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity

(2008) Ian J Majewski et al.   PLOS BIOLOGY

Polycomb Group Genes: Keeping Stem Cell Activity in Balance

(2008) Martin Sauvageau et al.   PLOS BIOLOGY