High frequency of RUNX1 biallelic alteration in acute myeloid leukemia secondary to familial platelet disorder

Syndromic thrombocytopenia and predisposition to acute myelogenous leukemia caused by constitutional microdeletions on chromosome 21q

(2008) M. Shinawi et al.   BLOOD

Five new pedigrees with inherited RUNX1 mutations causing familial platelet disorder with propensity to myeloid malignancy

(2008) C. J. Owen et al.   BLOOD

RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance

(2008) C. Roche-Lestienne et al.   BLOOD

Clinical phenotype of germline RUNX1 haploinsufficiency: from point mutations to large genomic deletions

(2008) Mylène Béri-Dexheimer et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A novel RUNX1 mutation in familial platelet disorder with propensity to develop myeloid malignancies

(2008) K. Kirito et al.   HAEMATOLOGICA

Somatic CEBPA Mutations Are a Frequent Second Event in Families With Germline CEBPA Mutations and Familial Acute Myeloid Leukemia

(2008) Thomas Pabst et al.   JOURNAL OF CLINICAL ONCOLOGY

Genetics of therapy-related myelodysplasia and acute myeloid leukemia

(2008) J Pedersen-Bjergaard et al.   LEUKEMIA