4.7 Editorial Material

TAFI: structured for self-destruction

Journal

BLOOD
Volume 112, Issue 7, Pages 2597-2598

Publisher

AMER SOC HEMATOLOGY
DOI: 10.1182/blood-2008-07-167734

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The elusive mystery surrounding the intrinsic thermal instability of TAFI has finally been solved, thanks to the determination of the first crystal structure of TAFI, which uncovers a highly dynamic local structure responsible for its self-destruction.

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