Article
Dermatology
Wei Zhu, Lingfeng Wu, Wenhua Xie, Gaoyue Zhang, Yanqin Gu, Yansong Hou, Yi He
Summary: A meta-analysis compared the wound infection rates between robotic-assisted radical prostatectomy and retropubic radical prostate surgery. The analysis showed that robotic-assisted surgery had significantly lower rates of surgical site wound infection and infected lymphoceles compared to retropubic surgery. However, caution is needed in interpreting the results due to small sample sizes in some of the included studies.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Surgery
Stamatios Katsimperis, Patrick Juliebo-Jones, Anthony Ta, Zafer Tandogdu, Osama Al-Bermani, Themistoklis Bellos, Francesco Esperto, Senol Tonyali, Iraklis Mitsogiannis, Andreas Skolarikos, Ioannis Varkarakis, Bhaskar K. Somani, Lazaros Tzelves
Summary: Radical prostatectomy has a significant impact on the anatomy of the male pelvis and urinary continence. Incontinence negatively affects patients' quality of life and psychological well-being. Various surgical techniques are used in robot-assisted radical prostatectomy (RARP) to preserve urinary continence.
FRONTIERS IN SURGERY
(2023)
Article
Urology & Nephrology
M. Stankovic, L. Wolff, T. Wieder, J. Mendes, B. Schumacher, M. Barro-Bejarano, C. Weber
Summary: The study aimed to evaluate the long-term oncological outcomes, complication rates, and early continence rates in patients treated with open retropubic radical prostatectomy (ORP). The results demonstrate that ORP is a surgical procedure that provides excellent oncological and early continence rates.
ACTAS UROLOGICAS ESPANOLAS
(2023)
Article
Oncology
Shuang Meng, Lihua Chen, Qinhe Zhang, Nan Wang, Ailian Liu
Summary: This study developed a novel mpMRI-based diagnostic model to predict surgical margins in prostate cancer patients, which showed higher specificity and predictive ability compared to a clinical-based model. The model can improve surgical planning and reduce the risk of positive surgical margins.
FRONTIERS IN ONCOLOGY
(2022)
Review
Pharmacology & Pharmacy
Christoph Wurnschimmel, Vera Panagl, Agostino Mattei, Christian Daniel Fankhauser
Summary: This article reviewed diagnostic methods to exclude leakage after radical prostatectomy and compared them with cystography. The results showed that ultrasound-guided assessment had promising agreement with cystography, while computerized tomography could detect more leakages, although the clinical consequences were not defined. Further studies are needed to identify patients at risk of leakage and to provide prospective comparisons of different ultrasound-guided approaches.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hannah Lamberg, Prasad R. Shankar, Karandeep Singh, Elaine M. Caoili, Arvin K. George, Caitlin Hackett, Anna Johnson, Matthew S. Davenport
Summary: This study aimed to evaluate the predictive ability and interrater agreement of MRI-based anatomic measurements, specifically the coronal membranous urethra length (MUL), for urinary continence after radical prostatectomy (RP). The study found that longer MUL was associated with improved continence outcomes after RP, while other MRI variables had no predictive ability. Age and baseline urinary function score were the only other predictive clinical variables. Interrater agreement of MRI variables was moderate among readers with specific training and poor among those without training.
Article
Oncology
Nicola D'Altilia, Vito Mancini, Ugo Giovanni Falagario, Leonardo Martino, Michele Di Nauta, Beppe Calo, Francesco Del Giudice, Satvir Basran, Benjamin Chung, Angelo Porreca, Lorenzo Bianchi, Riccardo Schiavina, Eugenio Brunocilla, Gian Maria Busetto, Carlo Bettocchi, Pasquale Annese, Luigi Cormio, Giuseppe Carrieri
Summary: The aim of this study was to compare continence recovery rates after robotic-assisted radical prostatectomy (RARP) and open surgery (RRP) using objective and subjective measurements. The results showed that RARP performed significantly better than RRP in terms of urinary continence based on both objective and subjective evaluations. The predictors of continence rates were found to be the bilateral nerve sparing technique and the robotic surgical approach.
Article
Multidisciplinary Sciences
Jaehun Jung, Gi Hwan Bae, Jae Heon Kim, Jaehong Kim
Summary: This study aimed to evaluate the clinical impact of robot-assisted radical prostatectomy (RARP) on health outcomes in Korean patients with prostate cancer (PCa). The study found that RARP had a higher risk of overall mortality within 3 and 12 months compared to radical prostatectomy (RP). The RARP group in hospitals with the largest PCa surgery volume had higher mortality rates and more surgical complications than the total RARP patients. The study suggests that RARP may not be superior to RP, possibly due to increased robotic surgery in the elderly.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, Research & Experimental
Mohammad Alyamani, Patrick Michael, Daniel Hettel, Lewis Thomas, Scott D. Lundy, Mike Berk, Mona Patel, Jianbo Li, Hooman Rashidi, Jesse K. McKenney, Eric A. Klein, Nima Sharifi
Summary: This study reveals that some men have enriched levels of testosterone (T) in the prostate region, which is associated with higher rates of prostate cancer recurrence. These findings suggest that the role of local androgen delivery in prostate cancer has been underestimated.
JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Oncology
Alberto Martini, Giorgio Gandaglia, Nicola Fossati, Simone Scuderi, Carlo Andrea Bravi, Elio Mazzone, Armando Stabile, Simone Scarcella, Daniele Robesti, Francesco Barletta, Vito Cucchiara, Vincenzo Mirone, Francesco Montorsi, Alberto Briganti
Summary: The study identified unfavorable positive surgical margin features that increase the risk of metastasis in men with more aggressive pathologic characteristics.
EUROPEAN UROLOGY ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shuang Meng, Wanting Gan, Lihua Chen, Nan Wang, Ailian Liu
Summary: This study aimed to investigate the predictive value of Intravoxel incoherent motion (IVIM) in positive surgical margins (PSMs) and Gleason score (GS) upgrading in prostate cancer patients after radical prostatectomy. The results showed that IVIM had good performance in predicting PSMs and GS upgrading. Combining IVIM with clinical factors improved the predictive ability for PSMs, which could contribute to clinical diagnosis and treatment.
Article
Multidisciplinary Sciences
Wang Shu, Wu Tao, Hu Chunyan, Fan Jie, Liu Yuan, Xu Yan, Zhang Huan, Xie Liang
Summary: The study found that Geriatric Nutritional Risk Index (GNRI) is correlated with postoperative recovery and complications in prostate cancer patients, and serves as an effective predictive marker.
Review
Urology & Nephrology
Xiaobo Wu, Chris Ho-Ming Wong, Giorgio Gandaglia, Peter Ka-Fung Chiu
Summary: Urinary incontinence is a common postoperative complication following robot-assisted radical prostatectomy (RARP) in patients with high-risk prostate cancer (HRPC). The recovery of urinary continence in HRPC patients after RARP is lower than that in intermediate/low-risk patients. Factors such as age, obesity, race, disease status, and surgical approaches can predict the recovery of continence. Special techniques like the NeuroSAFE technique and Retzius-Sparing approach also contribute to the reduction of incontinence in high-risk scenarios.
CURRENT OPINION IN UROLOGY
(2023)
Article
Medicine, General & Internal
Muhammad Ali Sohail, Gulshan Ali Memon, Shahida Baloch, Mumtaz Ali Chandio, Zameer Hussain Laghari
Summary: The study evaluated the complications related to open retro pubic radical prostatectomy in 75 subjects with localized prostate cancer, focusing on changes in urinary continence and quality of life indices. Results showed that patients with incontinence post-surgery benefited from pelvic floor exercises for improvement.
PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES
(2021)
Review
Oncology
Lijin Zhang, Hu Zhao, Bin Wu, Zhenlei Zha, Jun Yuan, Yejun Feng
Summary: This meta-analysis identified preoperative PSA, biopsy and pathological Gleason Scores, pathological stage, positive lymph node, extraprostatic extension, and seminal vesicle invasion as independent predictors of PSMs following radical prostatectomy. Factors such as age, BMI, prostate volume, and nerve sparing were found to have no effect on PSMs. The findings from this study may contribute to risk assessment and personalized therapy for PCa patients.
FRONTIERS IN ONCOLOGY
(2021)