Article
Public, Environmental & Occupational Health
Daina B. Esposito, Brian Bateman, Martha Werler, Loreen Straub, Helen Mogun, Sonia Hernandez-Diaz, Krista Huybrechts
Summary: Opioids may have an impact on placental abruption, preterm delivery, and small for gestational age, while showing no association with preeclampsia, according to a study using data from the US nationwide Medicaid Analytic Extract.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Medicine, General & Internal
Il-Yeo Jang, Hye-Ji Jung, Ji-Hee Sung, Suk-Joo Choi, Soo-Young Oh, Jung-Sun Kim, Cheong-Rae Roh
Summary: The indication for preterm delivery may affect the severity of placental inflammatory pathology and neonatal morbidity.
Article
Biochemistry & Molecular Biology
Monika Baczkowska, Magdalena Maria Dutsch-Wicherek, Ewa Przytula, Jan Faryna, Cezary Wojtyla, Mohamed Ali, Anna Knafel, Michal Ciebiera
Summary: This study evaluated the expression of B7-H4 protein in cases of placental abruption (PA) compared to retained placental tissue (RPT) and healthy controls. The results showed significantly higher expression of B7-H4 in the decidua and placental chorionic villus of PA patients. This suggests that B7-H4 may play an important role in restoring reproductive tract homeostasis.
Article
Medicine, General & Internal
Benshuo Cai, Yuheng Guan
Summary: This case report highlights a woman with pseudoexstrophy surviving recurrent placental abruption during pregnancy, emphasizing the importance of detailed imaging studies in female patients with this condition before pregnancy for risk assessment. Additionally, careful surgical procedures are essential to avoid complications in patients with pseudoexstrophy.
FRONTIERS IN MEDICINE
(2021)
Editorial Material
Public, Environmental & Occupational Health
Cande Ananth, Justin S. Brandt
Summary: The study found that intermittent use of opioids during pregnancy was associated with an increased risk of placental abruption, births that are small for gestational age, and preterm delivery, but not with preeclampsia. The authors used quantitative bias analysis to address potential biases and found that they did not strongly influence the associations. However, the study highlights the need for further research on the relationship between opioid use, pregnancy complications, and patient characteristics.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Yoshimitsu Wada, Hironori Takahashi, Yusuke Sasabuchi, Rie Usui, Manabu Ogoyama, Hirotada Suzuki, Akihide Ohkuchi, Hiroyuki Fujiwara
Summary: This study aimed to compare maternal outcomes between cesarean delivery and vaginal delivery in women with placental abruption and intrauterine fetal death. Results showed that bleeding during delivery was significantly greater in cesarean delivery than in vaginal delivery, but vaginal delivery was associated with severe complications such as maternal death and uterine rupture. Therefore, careful management is needed for women with placental abruption and intrauterine fetal death, regardless of the delivery route.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Multidisciplinary Sciences
Alexandra Sotiros, Dianne Thornhill, Miriam D. Post, Virginia D. Winn, Jennifer Armstrong
Summary: In our study, there was no obvious association between inflammation and placental pathology in preeclampsia and adverse neurodevelopmental outcomes at the 6-month corrected age. However, it suggests that maternal malperfusion at earlier gestational age may be a risk factor for worse outcomes.
Article
Medicine, General & Internal
Hee Jeung Lim, Jiyu Sun, Banhyang Min, Myungeun Song, Tae Hun Kim, Byoung Jae Kim, Kyu Ri Hwang, Taek Sang Lee, Hye Won Jeon, Sun Min Kim
Summary: Endometriosis is a major cause of infertility and can lead to adverse pregnancy outcomes. This study compared the clinical characteristics and pregnancy outcomes of women with and without endometriosis, finding that women with endometriosis had significantly more adverse pregnancy outcomes. Additionally, the endometriosis group had a higher rate of cesarean delivery and postpartum complications.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Obstetrics & Gynecology
Sarah E. Steane, Sophia L. Young, Vicki L. Clifton, Linda A. Gallo, Lisa K. Akison, Karen M. Moritz
Summary: The systematic review found that prenatal alcohol exposure increases the likelihood of placental abruption, decreases placental weight, and leads to changes in placental vasculature, DNA methylation, and molecular pathways. One study explored sex-specific placental outcomes in male and female infants separately. Further studies on the molecular mechanisms underlying alcohol-induced placental dysfunction and sex-specific placental adaptations are needed.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Review
Obstetrics & Gynecology
Yasuko Sano, Michi Kasai, Satoru Shinoda, Etsuko Miyagi, Shigeru Aoki
Summary: This study aimed to investigate possible factors indicating the need for early blood transfusion and the applicability of the Japanese scoring system for PPH in patients with PA-IUFD. The results showed that indicators such as fibrinogen levels, platelet count, D-dimer levels, FDP, and heart rate on admission may suggest the need for blood transfusion in patients with PA-IUFD.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Letter
Medicine, General & Internal
Peilin Zhang, Sylvia Dygulski, Farah Al-Sayyed, Beata Dygulska, Sanford Lederman
Summary: This study compared the prevalence of common pregnancy complications and placental pathologies by race and ethnicity among individuals treated at a community hospital in New York City.
Review
Pharmacology & Pharmacy
Hannah C. Zierden, Rachel L. Shapiro, Kevin DeLong, Davell M. Carter, Laura M. Ensign
Summary: Preterm birth is defined as delivery before 37 weeks of gestation, with 15 million infants born prematurely globally each year, increasing the risk of mortality and health challenges. While the only FDA approved therapy for preventing preterm birth in the U.S. has faced recent setbacks, interdisciplinary efforts are underway to develop next generation therapies to prevent preterm birth and save infant lives. This research aims to better identify women at risk for preterm birth, prevent premature labor, and ultimately improve outcomes for newborns.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Article
Obstetrics & Gynecology
Adi Goldbart, Gali Pariente, Eyal Sheiner, Tamar Wainstock
Summary: This study aims to identify the association between first pregnancy and subsequent placental abruption. The results show that complications during first pregnancy are associated with an increased risk of placental abruption, and the risk further increases with multiple complications. This suggests that the first pregnancy may serve as an opportunity to identify women at risk for future placental abruption.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Developmental Biology
Michal Levy, Michal Kovo, Emilie Ben-Ezry, Maya Torem, Hadar Shahaf, Noa Anchel, Jacob Bar, Letizia Schreiber, Eran Weiner
Summary: The study aimed to investigate the impact of maternal passive smoking (MPS) during pregnancy on placental pathology and pregnancy outcomes. Findings indicate that MPS is associated with higher rates of placental malperfusion lesions and adverse pregnancy outcomes, mediated via placental fetal vascular malperfusion. These results highlight the importance of patient counseling and further research in larger populations.
Article
Obstetrics & Gynecology
Reiko Suzuki, Natsumi Furuya, Junichi Hasegawa, Chika Homma, Yuriko Iwahata, Nao Suzuki
Summary: This article presents a case report of ultrasound pathological findings of placental abruption (PA) detected using superb microvascular imaging (SMI). SMI can contribute to a more accurate PA diagnosis that may lead to timely administration of obstetric intervention.
TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY
(2022)