The genetics of ocular disorders: Insights from the zebrafish

A complex regulatory network of transcription factors critical for ocular development and disease

(2011) Moulinath Acharya et al.   HUMAN MOLECULAR GENETICS

Spatiotemporal photolabeling of neutrophil trafficking during inflammation in live zebrafish

(2011) S. K. Yoo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum

(2011) Erica E Davis et al.   NATURE GENETICS

Establishment of a Transgenic Zebrafish Line for Superficial Skin Ablation and Functional Validation of Apoptosis Modulators In Vivo

(2011) Chi-Fang Chen et al.   PLoS One

Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme

(2011) G. Lupo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in Zebrafish lrp2 Result in Adult-Onset Ocular Pathogenesis That Models Myopia and Other Risk Factors for Glaucoma

(2011) Kerry N. Veth et al.   PLoS Genetics

Investigating regeneration and functional integration of CNS neurons: Lessons from zebrafish genetics and other fish species

(2010) Valerie C. Fleisch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aberrant forebrain signaling during early development underlies the generation of holoprosencephaly and coloboma

(2010) Patricia A. Gongal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Genetics of photoreceptor degeneration and regeneration in zebrafish

(2010) Susan E. Brockerhoff et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest

(2010) Kevin Curran et al.   DEVELOPMENTAL BIOLOGY

Exome sequencing: the sweet spot before whole genomes

(2010) J. K. Teer et al.   HUMAN MOLECULAR GENETICS

The Pax6b Homeodomain Is Dispensable for Pancreatic Endocrine Cell Differentiation in Zebrafish

(2010) Vincianne Verbruggen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The zebrafish mutant bumper shows a hyperproliferation of lens epithelial cells and fibre cell degeneration leading to functional blindness

(2010) Helia B. Schonthaler et al.   MECHANISMS OF DEVELOPMENT

Dually inducible TetON systems for tissue-specific conditional gene expression in zebrafish

(2010) F. Knopf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome

(2010) N. A. Zaghloul et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development and disease of the photoreceptor cilium

(2009) V Ramamurthy et al.   CLINICAL GENETICS

The primary cilium as a cellular signaling center: lessons from disease

(2009) Madeline A Lancaster et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish

(2009) Carrie McMahon et al.   DEVELOPMENTAL BIOLOGY

Nlcam modulates midline convergence during anterior neural plate morphogenesis

(2009) Katherine E. Brown et al.   DEVELOPMENTAL BIOLOGY

Early lens development in the zebrafish: A three-dimensional time-lapse analysis

(2009) Teri M.S. Greiling et al.   DEVELOPMENTAL DYNAMICS

DTA-mediated targeted ablation revealed differential interdependence of endocrine cell lineages in early development of zebrafish pancreas

(2009) Zhen Li et al.   DIFFERENTIATION

Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes

(2009) M. Asai-Coakwell et al.   HUMAN MOLECULAR GENETICS

Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies

(2009) M. Ye et al.   HUMAN MOLECULAR GENETICS

A novel model of retinal ablation demonstrates that the extent of rod cell death regulates the origin of the regenerated zebrafish rod photoreceptors

(2009) Jacob E. Montgomery et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Clinical spectrum of SIX3-associated mutations in holoprosencephaly: correlation between genotype, phenotype and function

(2009) F Lacbawan et al.   JOURNAL OF MEDICAL GENETICS

Spinal Interneurons Differentiate Sequentially from Those Driving the Fastest Swimming Movements in Larval Zebrafish to Those Driving the Slowest Ones

(2009) D. L. McLean et al.   JOURNAL OF NEUROSCIENCE

Inducible Male Infertility by Targeted Cell Ablation in Zebrafish Testis

(2009) Chia-Chun Hsu et al.   MARINE BIOTECHNOLOGY

Temporally-Controlled Site-Specific Recombination in Zebrafish

(2009) Stefan Hans et al.   PLoS One

Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure

(2009) J. D. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tbx2b is required for ultraviolet photoreceptor cell specification during zebrafish retinal development

(2009) Karen Alvarez-Delfin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early defects in photoreceptor outer segment morphogenesis in zebrafish ift57, ift88 and ift172 Intraflagellar Transport mutants

(2009) Sujita Sukumaran et al.   VISION RESEARCH

A Primer for Morpholino Use in Zebrafish

(2009) Brent R. Bill et al.   Zebrafish

Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye

(2008) Jiwoon Lee et al.   DEVELOPMENTAL BIOLOGY

Impairing retinoic acid signalling in the neural crest cells is sufficient to alter entire eye morphogenesis

(2008) Nicolas Matt et al.   DEVELOPMENTAL BIOLOGY

Mifepristone-inducible LexPR system to drive and control gene expression in transgenic zebrafish

(2008) Alexander Emelyanov et al.   DEVELOPMENTAL BIOLOGY

The eye organizes neural crest cell migration

(2008) Tobias Langenberg et al.   DEVELOPMENTAL DYNAMICS

Novel caspase-suicide proteins for tamoxifen-inducible apoptosis

(2008) Yuanyuan Chu et al.   GENESIS

Mutations in the human SIX3 gene in holoprosencephaly are loss of function

(2008) Sabina Domené et al.   HUMAN MOLECULAR GENETICS

Translational bypass of nonsense mutations in zebrafish rep1, pax2.1 and lamb1 highlights a viable therapeutic option for untreatable genetic eye disease

(2008) M. Moosajee et al.   HUMAN MOLECULAR GENETICS

The intraflagellar transport protein IFT57 is required for cilia maintenance and regulates IFT-particle-kinesin-II dissociation in vertebrate photoreceptors

(2008) B. L. Krock et al.   JOURNAL OF CELL SCIENCE

elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8

(2008) Yoshihiro Omori et al.   NATURE CELL BIOLOGY

Zinc Finger–Based Knockout Punches for Zebrafish Genes

(2008) Stephen C. Ekker   Zebrafish

Zebrafish: A model system for the study of eye genetics

(2007) J FADOOL et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Congenital cataracts and their molecular genetics

(2007) J. Fielding Hejtmancik   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY