4.4 Article

Will disruptive mood dysregulation disorder reduce false diagnosis of bipolar disorder in children?

Journal

BIPOLAR DISORDERS
Volume 14, Issue 5, Pages 488-496

Publisher

WILEY-BLACKWELL
DOI: 10.1111/j.1399-5618.2012.01029.x

Keywords

aggression; child; explosiveness; inpatient; irritability; mania; rages

Funding

  1. GlaxoSmithKline
  2. Bristol-Myers Squibb

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Margulies DM, Weintraub S, Basile J, Grover PJ, Carlson GA. Will disruptive mood dysregulation disorder reduce false diagnosis of bipolar disorder in children? Bipolar Disord 2012: 14: 488496. (c) 2012 The Authors Journal compilation (c) 2012 John Wiley & Sons A/S. Objectives: The frequency of diagnosis of bipolar disorder has risen dramatically in children and adolescents. The DSM-V Work Group has suggested a new diagnosis termed disruptive mood dysregulation disorder (DMDD) (formerly temper dysregulation disorder with dysphoria) to reduce the rate of false diagnosis of bipolar disorder in young people. We sought to determine if the application of the proposed diagnostic criteria for DMDD would reduce the rate of diagnosis of bipolar disorder in children. Patients and methods: Eighty-two consecutively hospitalized children, ages 5 to 12 years, on a childrens inpatient unit were rigorously diagnosed using admission interviews of the parents and the child, rating scales, and observation over the course of hospitalization. Results: Overall, 30.5% of inpatient children met criteria for DMDD by parent report, and 15.9% by inpatient unit observation. Fifty-six percent of inpatient children had parent-reported manic symptoms. Of those, 45.7% met criteria for DMDD by parent-report, though only 17.4% did when observed on the inpatient unit. Conclusion: Although DMDD does decrease the rate of diagnosis of bipolar disorder in children, how much depends on whether history or observation is used.

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