Physiological description of multivariate interdependencies between process parameters, morphology and physiology during fed-batch penicillin production

A novel method for fast and statistically verified morphological characterization of filamentous fungi

(2012) Andreas E. Posch et al.   FUNGAL GENETICS AND BIOLOGY

Combining light microscopy, dielectric spectroscopy, MALDI intact cell mass spectrometry, FTIR spectromicroscopy and multivariate data mining for morphological and physiological bioprocess characterization of filamentous organisms

(2012) Andreas E. Posch et al.   FUNGAL GENETICS AND BIOLOGY

Switching industrial production processes from complex to defined media: method development and case study using the example of Penicillium chrysogenum

(2012) Andreas E Posch et al.   Microbial Cell Factories

Science-based bioprocess design for filamentous fungi

(2012) Andreas E. Posch et al.   TRENDS IN BIOTECHNOLOGY

Scale-down of penicillin production in Penicillium chrysogenum

(2011) Lodewijk P. de Jonge et al.   Biotechnology Journal

Model-based analysis on the relationship of signal quality to real-time extraction of information in bioprocesses

(2011) Patrick Wechselberger et al.   BIOTECHNOLOGY PROGRESS

Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach

(2011) Rutger D Douma et al.   BMC Systems Biology

Intracellular metabolite determination in the presence of extracellular abundance: Application to the penicillin biosynthesis pathway in Penicillium chrysogenum

(2010) Rutger D. Douma et al.   BIOTECHNOLOGY AND BIOENGINEERING

Quality by design for biopharmaceuticals

(2009) Anurag S Rathore et al.   NATURE BIOTECHNOLOGY

Application of Multivariate Data Analysis for Identification and Successful Resolution of a Root Cause for a Bioprocessing Application

(2008) A.O. Kirdar et al.   BIOTECHNOLOGY PROGRESS

Bioprocess optimization using design-of-experiments methodology

(2008) Carl-Fredrik Mandenius et al.   BIOTECHNOLOGY PROGRESS

Isotopic non-stationary 13C gluconate tracer method for accurate determination of the pentose phosphate pathway split-ratio in Penicillium chrysogenum

(2008) Zheng Zhao et al.   METABOLIC ENGINEERING