Designing cost-effective biopharmaceutical facilities using mixed-integer optimization

A novel efficient optimisation system for purification process synthesis

(2012) Eleftheria M. Polykarpou et al.   BIOCHEMICAL ENGINEERING JOURNAL

A multi-level meta-heuristic algorithm for the optimisation of antibody purification processes

(2012) Ana S. Simaria et al.   BIOCHEMICAL ENGINEERING JOURNAL

Decisional tool to assess current and future process robustness in an antibody purification facility

(2012) Adam Stonier et al.   BIOTECHNOLOGY PROGRESS

Integration of stochastic simulation with multivariate analysis: Short-term facility fit prediction

(2012) Adam Stonier et al.   BIOTECHNOLOGY PROGRESS

Optimal synthesis of chromatographic trains for downstream protein processing

(2011) Eleftheria M. Polykarpou et al.   BIOTECHNOLOGY PROGRESS

An MILP formulation for the synthesis of protein purification processes

(2011) Eleftheria M. Polykarpou et al.   CHEMICAL ENGINEERING RESEARCH & DESIGN

Industrialization of mAb production technology: The bioprocessing industry at a crossroads

(2010) Brian Kelley   mAbs

Efficient MILP formulations for the simultaneous optimal peptide tag design and downstream processing synthesis

(2009) João M. Natali et al.   AICHE JOURNAL

Decision-Support Tool for Assessing Biomanufacturing Strategies under Uncertainty: Stainless Steel versus Disposable Equipment for Clinical Trial Material Preparation

(2005) Suzanne S. Farid et al.   BIOTECHNOLOGY PROGRESS

Application of a Decision-Support Tool to Assess Pooling Strategies in Perfusion Culture Processes under Uncertainty

(2005) Ai Chye Lim et al.   BIOTECHNOLOGY PROGRESS

MINLP Models for the Synthesis of Optimal Peptide Tags and Downstream Protein Processing

(2005) Evangelos Simeonidis et al.   BIOTECHNOLOGY PROGRESS