Chromatography process development in the quality by design paradigm I: Establishing a high-throughput process development platform as a tool for estimating “characterization space” for an ion exchange chromatography step

High-throughput process development of chromatography steps: Advantages and limitations of different formats used

(2012) Karol M. Łącki   Biotechnology Journal

Predicting protein dynamic binding capacity from batch adsorption tests

(2012) Giorgio Carta   Biotechnology Journal

Influence of protein and stationary phase properties on protein–matrix-interaction in cation exchange chromatography

(2011) Marina Urmann et al.   JOURNAL OF CHROMATOGRAPHY A

High-throughput process development for biopharmaceutical drug substances

(2011) Rahul Bhambure et al.   TRENDS IN BIOTECHNOLOGY

Defining process design space for a hydrophobic interaction chromatography (HIC) purification step: Application of quality by design (QbD) principles

(2010) Canping Jiang et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput isotherm determination and thermodynamic modeling of protein adsorption on mixed mode adsorbents

(2010) Beckley K. Nfor et al.   JOURNAL OF CHROMATOGRAPHY A

Use of the design-of-experiments approach for the development of a refolding technology for progenipoietin-1, a recombinant human cytokine fusion protein fromEscherichia coliinclusion bodies

(2009) Denis M. Boyle et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Review: Microscale methods for high-throughput chromatography development in the pharmaceutical industry

(2009) Sunil Chhatre et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Comparison of agarose and dextran-grafted agarose strong ion exchangers for the separation of protein aggregates

(2009) Eric J. Suda et al.   JOURNAL OF CHROMATOGRAPHY A

Quality by design for biopharmaceuticals

(2009) Anurag S Rathore et al.   NATURE BIOTECHNOLOGY

Roadmap for implementation of quality by design (QbD) for biotechnology products

(2009) Anurag S. Rathore   TRENDS IN BIOTECHNOLOGY

Micro biochemical engineering to accelerate the design of industrial-scale downstream processes for biopharmaceutical proteins

(2008) N.J. Titchener-Hooker et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput screening of chromatographic separations: II. Hydrophobic interaction

(2008) Jack F. Kramarczyk et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput screening of chromatographic separations: I. Method development and column modeling

(2008) Jonathan L. Coffman et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-Throughput Process Development: Determination of Dynamic Binding Capacity Using Microtiter Filter Plates Filled with Chromatography Resin

(2008) T. Bergander et al.   BIOTECHNOLOGY PROGRESS

Defining Process Design Space for Biotech Products: Case Study of Pichia pastoris Fermentation

(2008) J. Harms et al.   BIOTECHNOLOGY PROGRESS

High Throughput Screening for the Design and Optimization of Chromatographic Processes – Miniaturization, Automation and Parallelization of Breakthrough and Elution Studies

(2008) M. Wiendahl et al.   CHEMICAL ENGINEERING & TECHNOLOGY

High Throughput Screening for the Design and Optimization of Chromatographic Processes: Automated Optimization of Chromatographic Phase Systems

(2008) A. Susanto et al.   CHEMICAL ENGINEERING & TECHNOLOGY