A dynamic mathematical model for monoclonal antibody N-linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus

An investigation of intracellular glycosylation activities in CHO cells: Effects of nucleotide sugar precursor feeding

(2010) Niki S.C. Wong et al.   BIOTECHNOLOGY AND BIOENGINEERING

Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns

(2010) Ioscani Jimenez del Val et al.   BIOTECHNOLOGY PROGRESS

Systematic development of predictive mathematical models for animal cell cultures

(2010) Cleo Kontoravdi et al.   COMPUTERS & CHEMICAL ENGINEERING

Naturally occurring glycan forms of human immunoglobulins G1 and G2

(2010) Gregory C. Flynn et al.   MOLECULAR IMMUNOLOGY

What's fueling the biotech engine—2009–2010

(2010) Saurabh Aggarwal   NATURE BIOTECHNOLOGY

Membrane Traffic Within the Golgi Apparatus

(2009) Benjamin S. Glick et al.   Annual Review of Cell and Developmental Biology

Sorting out glycosylation enzymes in the Golgi apparatus

(2009) Tommy Nilsson et al.   FEBS LETTERS

Optimal and consistent protein glycosylation in mammalian cell culture

(2009) P. Hossler et al.   GLYCOBIOLOGY

Quality by design for biopharmaceuticals

(2009) Anurag S Rathore et al.   NATURE BIOTECHNOLOGY

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

Influence of intracellular nucleotide and nucleotide sugar contents on recombinant interferon-γ glycosylation during batch and fed-batch cultures of CHO cells

(2008) N. Kochanowski et al.   BIOTECHNOLOGY AND BIOENGINEERING

Terminal sugars of Fc glycans influence antibody effector functions of IgGs

(2008) T Shantha Raju   CURRENT OPINION IN IMMUNOLOGY

Capillary electrophoresis-electrospray ionization mass spectrometry for rapid and sensitive N-glycan analysis of glycoproteins as 9-fluorenylmethyl derivatives

(2008) M. Nakano et al.   GLYCOBIOLOGY

The effect of Fc glycan forms on human IgG2 antibody clearance in humans

(2008) X. Chen et al.   GLYCOBIOLOGY

Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides

(2008) Johannes Stadlmann et al.   PROTEOMICS

The N-Linked sugar chains of human immunoglobulin G: Their unique pattern, and their functional roles

(2007) Akira Kobata   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS