Homology modeling, molecular docking and spectra assay studies of sterol 14α-demethylase from Penicillium digitatum

Structural basis for conservation in the CYP51 family

(2010) Galina I. Lepesheva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cytochrome P450 enzymes in the fungal kingdom

(2010) B. Črešnar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Novel conformationally restricted triazole derivatives with potent antifungal activity

(2010) Wenya Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structural Insights into Inhibition of Sterol 14α-Demethylase in the Human PathogenTrypanosoma cruzi

(2010) Galina I. Lepesheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Based Rational Screening of Novel Hit Compounds with Structural Diversity for Cytochrome P450 Sterol 14α-Demethylase from Penicillium digitatum

(2010) Qingye Zhang et al.   Journal of Chemical Information and Modeling

Structural Basis of Human CYP51 Inhibition by Antifungal Azoles

(2010) Natallia Strushkevich et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole

(2010) Chiung-Kuang Chen et al.   PLoS Neglected Tropical Diseases

Three-Dimensional Model of Lanosterol 14 -Demethylase from Cryptococcus neoformans: Active-Site Characterization and Insights into Azole Binding

(2009) C. Sheng et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal Structures of Trypanosoma brucei Sterol 14α-Demethylase and Implications for Selective Treatment of Human Infections

(2009) Galina I. Lepesheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CYP51: A Major Drug Target in the Cytochrome P450 Superfamily

(2008) Galina I. Lepesheva et al.   LIPIDS