High-throughput nucleoside phosphate monitoring in mammalian cell fed-batch cultivation using quantitative matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Performance monitoring of a mammalian cell based bioprocess using Raman spectroscopy

(2013) Boyan Li et al.   ANALYTICA CHIMICA ACTA

Self-Aliquoting Microarray Plates for Accurate Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

(2013) Martin Pabst et al.   ANALYTICAL CHEMISTRY

Comparison of control strategies for fed-batch culture of hybridoma cells based on on-line monitoring of oxygen uptake rate, optical cell density and glucose concentration

(2013) Antoni Casablancas et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Metabolic profiling reveals that time related physiological changes in mammalian cell perfusion cultures are bioreactor scale independent

(2013) Spyros I. Vernardis et al.   METABOLIC ENGINEERING

Mass spectrometry based analysis of nucleotides, nucleosides, and nucleobases—application to feed supplements

(2012) Stefan Neubauer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Metabolite profiling of CHO cells with different growth characteristics

(2012) Stefanie Dietmair et al.   BIOTECHNOLOGY AND BIOENGINEERING

The need for innovation in biomanufacturing

(2012) Uwe Gottschalk et al.   NATURE BIOTECHNOLOGY

Systems biotechnology of animal cells: the road to prediction

(2012) Nuno Carinhas et al.   TRENDS IN BIOTECHNOLOGY

Defining viability in mammalian cell cultures

(2011) Susan M. Browne et al.   BIOTECHNOLOGY LETTERS

Estimating cell specific oxygen uptake and carbon dioxide production rates for mammalian cells in perfusion culture

(2011) Chetan T. Goudar et al.   BIOTECHNOLOGY PROGRESS

Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth

(2011) Michael Taschwer et al.   JOURNAL OF BIOTECHNOLOGY

Towards quantitative metabolomics of mammalian cells: Development of a metabolite extraction protocol

(2010) Stefanie Dietmair et al.   ANALYTICAL BIOCHEMISTRY

Nucleotide and Nucleotide Sugar Analysis by Liquid Chromatography-Electrospray Ionization-Mass Spectrometry on Surface-Conditioned Porous Graphitic Carbon

(2010) Martin Pabst et al.   ANALYTICAL CHEMISTRY

Comparison of viable cell concentration estimation methods for a mammalian cell cultivation process

(2010) M. Aehle et al.   CYTOTECHNOLOGY

Cell culture metabolomics: applications and future directions

(2010) Miroslava Čuperlović-Culf et al.   DRUG DISCOVERY TODAY

Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: Overexpression of malate dehydrogenase II

(2010) William P.K. Chong et al.   JOURNAL OF BIOTECHNOLOGY

Metabolomics-based identification of apoptosis-inducing metabolites in recombinant fed-batch CHO culture media

(2010) William P.K. Chong et al.   JOURNAL OF BIOTECHNOLOGY

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Recent advances in large-scale production of monoclonal antibodies and related proteins

(2010) Abhinav A. Shukla et al.   TRENDS IN BIOTECHNOLOGY

Metabolomics for high-resolution monitoring of the cellular physiological state in cell culture engineering

(2009) Panagiotis K. Chrysanthopoulos et al.   METABOLIC ENGINEERING

Metabolic flux analysis in mammalian cell culture

(2009) Lake-Ee Quek et al.   METABOLIC ENGINEERING

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

(2009) Arun Sreekumar et al.   NATURE

On-Line Monitoring of Microbial Volatile Metabolites by Proton Transfer Reaction-Mass Spectrometry

(2008) M. Bunge et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Quantitative profiling of nucleotides and related phosphate-containing metabolites in cultured mammalian cells by liquid chromatography tandem electrospray mass spectrometry

(2008) Rebecca L. Cordell et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

(Re)defining biopharmaceutical

(2008) Ronald A Rader   NATURE BIOTECHNOLOGY

Quantitative metabolomics using NMR

(2008) David S. Wishart   TRAC-TRENDS IN ANALYTICAL CHEMISTRY