Genetically encoded reactive oxygen species (ROS) and redox indicators

Respective Contribution of Mitochondrial Superoxide and pH to Mitochondria-targeted Circularly Permuted Yellow Fluorescent Protein (mt-cpYFP) Flash Activity

(2013) Lan Wei-LaPierre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox

(2013) Edward Avezov et al.   JOURNAL OF CELL BIOLOGY

Endoplasmic reticulum: reduced and oxidized glutathione revisited

(2013) J. Birk et al.   JOURNAL OF CELL SCIENCE

Superoxide constitutes a major signal of mitochondrial superoxide flash

(2013) Xing Zhang et al.   LIFE SCIENCES

Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration

(2013) Nick R. Love et al.   NATURE CELL BIOLOGY

HyPer-3: A Genetically Encoded H2O2 Probe with Improved Performance for Ratiometric and Fluorescence Lifetime Imaging

(2012) Dmitry S. Bilan et al.   ACS Chemical Biology

Spatial and Temporal Analysis of NADPH Oxidase-Generated Hydrogen Peroxide Signals by Novel Fluorescent Reporter Proteins

(2012) Balázs Enyedi et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Biology on the rise

(2012) Johannes M. Herrmann et al.   BIOLOGICAL CHEMISTRY

Redox-sensitive YFP sensors monitor dynamic nuclear and cytosolic glutathione redox changes

(2012) Michèle Dardalhon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondria-targeted cpYFP: pH or superoxide sensor?

(2012) Emilie Quatresous et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mitochondrial Superoxide Production Negatively Regulates Neural Progenitor Proliferation and Cerebral Cortical Development

(2012) Yan Hou et al.   STEM CELLS

Mitochondrial ‘flashes’: a radical concept repHined

(2012) Markus Schwarzländer et al.   TRENDS IN CELL BIOLOGY

The circularly permuted yellow fluorescent protein cpYFP that has been used as a superoxide probe is highly responsive to pH but not superoxide in mitochondria: implications for the existence of superoxide ‘flashes’

(2011) Markus Schwarzländer et al.   BIOCHEMICAL JOURNAL

Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor

(2011) Yin Pun Hung et al.   Cell Metabolism

In Vivo Mapping of Hydrogen Peroxide and Oxidized Glutathione Reveals Chemical and Regional Specificity of Redox Homeostasis

(2011) Simone C. Albrecht et al.   Cell Metabolism

Unraveling the Biological Roles of Reactive Oxygen Species

(2011) Michael P. Murphy et al.   Cell Metabolism

Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals

(2011) Huaqiang Fang et al.   CELL RESEARCH

Measuring EGSH and H2O2 with roGFP2-based redox probes

(2011) Bruce Morgan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Exploring real-time in vivo redox biology of developing and aging Caenorhabditis elegans

(2011) Patricia Back et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dynamic Regulation of the Mitochondrial Proton Gradient during Cytosolic Calcium Elevations

(2011) Damon Poburko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Superoxide Flashes

(2011) Qi Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Real-time monitoring of redox changes in the mammalian endoplasmic reticulum

(2011) M. van Lith et al.   JOURNAL OF CELL SCIENCE

Glutamate Transport Decreases Mitochondrial pH and Modulates Oxidative Metabolism in Astrocytes

(2011) G. Azarias et al.   JOURNAL OF NEUROSCIENCE

Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk

(2011) Oksana Ivashchenko et al.   MOLECULAR BIOLOGY OF THE CELL

Hydrogen Peroxide Probes Directed to Different Cellular Compartments

(2011) Mikalai Malinouski et al.   PLoS One

Fluorescent Protein-Based Redox Probes

(2010) Andreas J. Meyer et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox State of the Endoplasmic Reticulum Is Controlled by Ero1L-alpha and Intraluminal Calcium

(2010) Balázs Enyedi et al.   ANTIOXIDANTS & REDOX SIGNALING

A genetically encoded sensor for H2O2 with expanded dynamic range

(2010) Kseniya N. Markvicheva et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A Novel Fluorescent Sensor Protein for Visualization of Redox States in the Cytoplasm and in Peroxisomes

(2010) T. Yano et al.   MOLECULAR AND CELLULAR BIOLOGY

Nox4-Derived H2O2 Mediates Endoplasmic Reticulum Signaling through Local Ras Activation

(2010) R.-F. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Superoxide Flashes in Mouse Skeletal Muscle Are Produced by Discrete Arrays of Active Mitochondria Operating Coherently

(2010) Sandrine Pouvreau   PLoS One

Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases

(2009) Marcus Gutscher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Development of a Family of Redox-Sensitive Green Fluorescent Protein Indicators for Use in Relatively Oxidizing Subcellular Environments†‡

(2008) Jeremy R. Lohman et al.   BIOCHEMISTRY

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Redox Environment in the Mitochondrial Intermembrane Space Is Maintained Separately from the Cytosol and Matrix

(2008) Jingjing Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

Real-time imaging of the intracellular glutathione redox potential

(2008) Marcus Gutscher et al.   NATURE METHODS

High-Resolution Imaging of Redox Signaling in Live Cells Through an Oxidation-Sensitive Yellow Fluorescent Protein

(2008) G. Maulucci et al.   Science Signaling