Molecular signatures from omics data: From chaos to consensus

Novel Computational Approaches to Polypharmacology as a Means to Define Responses to Individual Drugs

(2011) Lei Xie et al.   Annual Review of Pharmacology and Toxicology

The identification of gene expression profiles associated with progression of human diabetic neuropathy

(2011) Junguk Hur et al.   BRAIN

Boosting Signal-to-Noise in Complex Biology: Prior Knowledge Is Power

(2011) Trey Ideker et al.   CELL

A pharmacogenomic method for individualized prediction of drug sensitivity

(2011) A. L. Cohen et al.   Molecular Systems Biology

The sequence read archive: explosive growth of sequencing data

(2011) Y. Kodama et al.   NUCLEIC ACIDS RESEARCH

Integrated Analyses of Copy Number Variations and Gene Expression in Lung Adenocarcinoma

(2011) Tzu-Pin Lu et al.   PLoS One

Metabolome in progression to Alzheimer's disease

(2011) M Orešič et al.   Translational Psychiatry

Variable selection and regression analysis for graph-structured covariates with an application to genomics

(2010) Caiyan Li et al.   Annals of Applied Statistics

Tackling the widespread and critical impact of batch effects in high-throughput data

(2010) Jeffrey T. Leek et al.   NATURE REVIEWS GENETICS

ArrayExpress update--an archive of microarray and high-throughput sequencing-based functional genomics experiments

(2010) H. Parkinson et al.   NUCLEIC ACIDS RESEARCH

Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways

(2010) Jeremy A. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probabilistic integrative modeling of genome-scale metabolic and regulatory networks inEscherichia coliandMycobacterium tuberculosis

(2010) Sriram Chandrasekaran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of Metabolic Signatures for Predicting Whole Organism Toxicology

(2010) Adam Hines et al.   TOXICOLOGICAL SCIENCES

Identifying Tightly Regulated and Variably Expressed Networks by Differential Rank Conservation (DIRAC)

(2010) James A. Eddy et al.   PLoS Computational Biology

Making Informed Choices about Microarray Data Analysis

(2010) Mark Reimers   PLoS Computational Biology

An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer

(2010) Rod K. Nibbe et al.   PLoS Computational Biology

Cardiac biomarkers and the case for point-of-care testing

(2009) Barry McDonnell et al.   CLINICAL BIOCHEMISTRY

A Genomic Approach to Improve Prognosis and Predict Therapeutic Response in Chronic Lymphocytic Leukemia

(2009) D. R. Friedman et al.   CLINICAL CANCER RESEARCH

A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease

(2009) Nicola Greenberg et al.   ELECTROPHORESIS

Covariance-regularized regression and classification for high dimensional problems

(2009) Daniela M. Witten et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

A systems approach to prion disease

(2009) Daehee Hwang et al.   Molecular Systems Biology

Disease signatures are robust across tissues and experiments

(2009) Joel T Dudley et al.   Molecular Systems Biology

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

Markers of dispute

(2009) Virginia Hughes   NATURE MEDICINE

Stage Dependent Aberrant Regulation of Cytokine-STAT Signaling in Murine Systemic Lupus Erythematosus

(2009) Matthew B. Hale et al.   PLoS One

Network-constrained regularization and variable selection for analysis of genomic data

(2008) C. Li et al.   BIOINFORMATICS

Merging microarray data from separate breast cancer studies provides a robust prognostic test

(2008) Lei Xu et al.   BMC BIOINFORMATICS

Ovarian Cancer Early Detection Claims Are Biased

(2008) M. McIntosh et al.   CLINICAL CANCER RESEARCH

Beyond data integration

(2008) Ted Slater et al.   DRUG DISCOVERY TODAY

Alzheimer's disease beyond the genomic era: nuclear magnetic resonance (NMR) spectroscopy-based metabolomics

(2008) Ignasi Barba et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Identification of a 5-Protein Biomarker Molecular Signature for Predicting Alzheimer's Disease

(2008) Martín Gómez Ravetti et al.   PLoS One