Birth, life and death of nascent polypeptide chains

The ribosomal tunnel as a functional environment for nascent polypeptide folding and translational stalling

(2011) Daniel N Wilson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Functional Half-Life of an mRNA Depends on the Ribosome Spacing in an Early Coding Region

(2011) Margit Pedersen et al.   JOURNAL OF MOLECULAR BIOLOGY

Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center

(2011) Haripriya Ramu et al.   MOLECULAR CELL

Divergent stalling sequences sense and control cellular physiology

(2010) Koreaki Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Early targeting events during membrane protein biogenesis in Escherichia coli

(2010) Eitan Bibi   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Sec translocase

(2010) David J.F. du Plessis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The ribosome-bound Hsp70 homolog Ssb of Saccharomyces cerevisiae

(2010) Kristin Peisker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure and function of the molecular chaperone Trigger Factor

(2010) Anja Hoffmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Post-translational myristoylation: Fat matters in cellular life and death

(2010) Dale D.O. Martin et al.   BIOCHIMIE

An Evolutionarily Conserved Mechanism for Controlling the Efficiency of Protein Translation

(2010) Tamir Tuller et al.   CELL

A Role for Codon Order in Translation Dynamics

(2010) Gina Cannarozzi et al.   CELL

Participation of lectin chaperones and thiol oxidoreductases in protein folding within the endoplasmic reticulum

(2010) Lori A Rutkevich et al.   CURRENT OPINION IN CELL BIOLOGY

Protein folding on the ribosome

(2010) Lisa D Cabrita et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

(2010) Nora Vázquez-Laslop et al.   EMBO JOURNAL

Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling

(2010) M. A. Skabkin et al.   GENES & DEVELOPMENT

The Ribosome Comes Alive

(2010) Joachim Frank   ISRAEL JOURNAL OF CHEMISTRY

Sequence Requirements for Ribosome Stalling by the Arginine Attenuator Peptide

(2010) Christina C. Spevak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Folding Zone in the Ribosomal Exit Tunnel for Kv1.3 Helix Formation

(2010) Li Wei Tu et al.   JOURNAL OF MOLECULAR BIOLOGY

Nα-Acetylation of yeast ribosomal proteins and its effect on protein synthesis

(2010) Masahiro Kamita et al.   Journal of Proteomics

Transient Tertiary Structure Formation within the Ribosome Exit Port

(2010) Edward P. O’Brien et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recognition of a signal peptide by the signal recognition particle

(2010) Claudia Y. Janda et al.   NATURE

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

(2010) Mario H. Bengtson et al.   NATURE

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor

(2010) Leandro F Estrozi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

α-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel

(2010) Shashi Bhushan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution

(2010) J.-P. Armache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localization of eukaryote-specific ribosomal proteins in a 5.5-A cryo-EM map of the 80S eukaryotic ribosome

(2010) J.-P. Armache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Eukaryotic Ribosome

(2010) A. Ben-Shem et al.   SCIENCE

N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

(2010) C.-S. Hwang et al.   SCIENCE

Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1

(2010) J. Rabl et al.   SCIENCE

Protein Acetylation in Archaea, Bacteria, and Eukaryotes

(2010) Jörg Soppa   ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Recent mechanistic insights into eukaryotic ribosomes

(2009) Marina V Rodnina et al.   CURRENT OPINION IN CELL BIOLOGY

Nascent Peptide-dependent Translation Arrest Leads to Not4p-mediated Protein Degradation by the Proteasome

(2009) Lyudmila N. Dimitrova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Plasticity of a Translation Arrest Motif Yields Insights into Nascent Polypeptide Recognition inside the Ribosome Tunnel

(2009) Mee-Ngan Yap et al.   MOLECULAR CELL

The eIF3 Interactome Reveals the Translasome, a Supercomplex Linking Protein Synthesis and Degradation Machineries

(2009) Zhe Sha et al.   MOLECULAR CELL

What recent ribosome structures have revealed about the mechanism of translation

(2009) T. Martin Schmeing et al.   NATURE

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

(2009) Günter Kramer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tertiary interactions within the ribosomal exit tunnel

(2009) Andrey Kosolapov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transient ribosomal attenuation coordinates protein synthesis and co-translational folding

(2009) Gong Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multiple conformational switches in a GTPase complex control co-translational protein targeting

(2009) Xin Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insight into Nascent Polypeptide Chain-Mediated Translational Stalling

(2009) B. Seidelt et al.   SCIENCE

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

(2009) T. Becker et al.   SCIENCE

Cotranslational processing mechanisms: towards a dynamic 3D model

(2009) Carmela Giglione et al.   TRENDS IN BIOCHEMICAL SCIENCES

N-glycan structures: recognition and processing in the ER

(2009) Markus Aebi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Folding at the rhythm of the rare codon beat

(2008) Monica Marin   Biotechnology Journal

Role of the ribosome in protein folding

(2008) Debasis Das et al.   Biotechnology Journal

A structural view of translation initiation in bacteria

(2008) A. Simonetti et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Combining experiment and simulation in protein folding: closing the gap for small model systems

(2008) R Dustin Schaeffer et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein Folding by Domain V of Escherichia coli 23S rRNA: Specificity of RNA-Protein Interactions

(2008) D. Samanta et al.   JOURNAL OF BACTERIOLOGY

Conserved Residues Asp16 and Pro24 of TnaC-tRNAPro Participate in Tryptophan Induction of tna Operon Expression

(2008) L. R. Cruz-Vera et al.   JOURNAL OF BACTERIOLOGY

Effects on Translation Pausing of Alterations in Protein and RNA Components of the Ribosome Exit Tunnel

(2008) M. G. Lawrence et al.   JOURNAL OF BACTERIOLOGY

Synonymous Mutations and Ribosome Stalling Can Lead to Altered Folding Pathways and Distinct Minima

(2008) Chung-Jung Tsai et al.   JOURNAL OF MOLECULAR BIOLOGY

A peptide deformylase–ribosome complex reveals mechanism of nascent chain processing

(2008) Rouven Bingel-Erlenmeyer et al.   NATURE

Rare Codons Cluster

(2008) Thomas F. Clarke et al.   PLoS One

Modulating the activity of the peptidyl transferase center of the ribosome

(2008) M. Beringer   RNA

A pause for thought along the co-translational folding pathway

(2008) Anton A. Komar   TRENDS IN BIOCHEMICAL SCIENCES

Yeast Nα-terminal acetyltransferases are associated with ribosomes

(2007) Bogdan Polevoda et al.   JOURNAL OF CELLULAR BIOCHEMISTRY