Characterization of antibody drug conjugate positional isomers at cysteine residues by peptide mapping LC–MS analysis

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Title
Characterization of antibody drug conjugate positional isomers at cysteine residues by peptide mapping LC–MS analysis
Authors
Keywords
Antibody drug conjugates, Brentuximab vedotin, Drug-loaded peptide mapping, IdeS, Liquid chromatography mass spectrometry, Payload positional isomers
Journal
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
Volume 981-982, Issue -, Pages 9-13
Publisher
Elsevier BV
Online
2014-12-24
DOI
10.1016/j.jchromb.2014.12.017

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