Article
Energy & Fuels
Yang Chen, Yanan Yin, Jianlong Wang
Summary: The study found that pretreating Laminaria japonica with gamma irradiation can enhance hydrogen production by dark fermentation. Irradiation at 10-30 kGy effectively breaks down the seaweed's structure and increases the concentration of organic compounds, but doses above 30 kGy may have a negative impact on hydrogen production efficiency.
Article
Biotechnology & Applied Microbiology
Zhipeng Li, Zeping Du, Hebin Li, Yanhong Chen, Mingjing Zheng, Zedong Jiang, Xiping Du, Hui Ni, Yanbing Zhu
Summary: Marine bacterium Microbulbifer sp. ALW1 can effectively degrade Laminaria japonica thallus fragments and produce various enzymes. ALW1 has unique cell morphology, physiological, and biochemical characteristics compared to other related species. The complete genome of ALW1 has been sequenced and can be utilized in potential industrial applications.
Article
Food Science & Technology
Qiulin Yue, Zhongjian Wang, Fupeng Yu, Xueyang Tang, Le Su, Song Zhang, Xin Sun, Kunlun Li, Chen Zhao, Lin Zhao
Summary: This study found that fermentation by adding Saccharomyces cerevisiae and Lactiplantibacillus to Laminaria japonica significantly improved its nutritional and medicinal value, and altered its metabolite profiles.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Xiao-Hui Sun, Xiu-Lan Chen, Xiao-Fei Wang, Xin-Ru Zhang, Xiao-Meng Sun, Mei-Ling Sun, Xi-Ying Zhang, Yu-Zhong Zhang, Yu-Qiang Zhang, Fei Xu
Summary: An efficient and cost-effective process for the production of alginate oligosaccharides (AOs) directly from Laminaria japonica roots was established using the strain Pseudoalteromonas agarivorans A3. The study showed that A3 could secrete alginate lyases to degrade L. japonica, and by optimizing the production and hydrolysis parameters, AOs were efficiently produced from the fermentation broth supernatant. The generated AOs had a wide range in size and showed potential for industrial and agricultural applications.
MICROBIAL CELL FACTORIES
(2023)
Article
Agricultural Engineering
Zhuhong Ding, Lianyi Zhang, Huijing Mo, Yijun Chen, Xin Hu
Summary: Limited investigations have been conducted on preparing and applying alga-based hydrochars using microwave-assisted catalytic hydrothermal carbonization (MA-CHTC). The study successfully prepared hydrochars from Laminaria japonica biomass with various catalysts and showed improved Pb(II) adsorption capacities due to the synergetic chemical activation of the spiked catalysts, highlighting the potential for tailored design of engineered hydrochars for specific applications.
BIORESOURCE TECHNOLOGY
(2021)
Article
Nutrition & Dietetics
Xueqian Zhang, Changyu Su, Cui Cao, Guiping Gong, Linjuan Huang, Zhongfu Wang, Shuang Song, Beiwei Zhu
Summary: Intake of Laminaria japonica can balance gut microbiota composition, enhance the ability of microbiota to utilize alginate, and have positive impacts on human health.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Medicinal
Qianru Sun, Jiaxuan Fang, Ziwen Wang, Zixin Song, Jiman Geng, Dongdong Wang, Changtao Wang, Meng Li
Summary: Fermented Laminaria japonica has protective and reparative effects on UVB-induced epidermal inflammation by removing excess reactive oxygen species, increasing antioxidant enzyme content, and reducing the secretion of inflammatory factors. It activates signaling pathways and inhibits gene expression levels to alleviate cellular oxidative stress and inflammatory response.
Article
Biochemistry & Molecular Biology
Xueqian Zhang, Ying You, LiLong Wang, Chunqing Ai, Linjuan Huang, Songtao Wang, Zhongfu Wang, Shuang Song, Beiwei Zhu
Summary: Previous studies have shown that fucoidan can resist high-fat-diet-induced obesity by modulating the composition of gut microbiota. In this study, the anti-obesity effects of fucoidan were compared between mice with different gut microbiota communities. The results demonstrated that mice with different initial gut microbiota responded differently to fucoidan supplementation, and certain gut bacteria were required for the anti-obesity effects.
Article
Environmental Sciences
Kang Song, Zhouyang Li, Lu Li, Xiaoli Zhao, Min Deng, Xu Zhou, Yifeng Xu, Lai Peng, Renhui Li, Qilin Wang
Summary: This study investigated the methane production potential of algal biomass by anaerobic digestion with the addition of peroxymonosulfate (PMS), and analyzed the removal of microcystin. The results showed that anaerobic digestion could recover energy from algal source in the form of methane gas, and the presence of microcystin did not affect methane production. The study also revealed a microcystin removal rate of over 99%.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Physical
Do-Hyung Kim, In-Seung Jo, Beom-Jung Kang, Byung-Don Lee, Sunil Kumar, Sang-Hyoun Kim, Jeong-Jun Yoon
Summary: This study investigated the properties of hydrolysates obtained from acid and alkali hydrolysis for bio-hydrogen production. Results showed that 1.0% H2SO4 hydrolysate had the highest hydrogen production efficiency, while hydrogen production and metabolite distribution depended on the sugars and by-product composition in the hydrolysate.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Agricultural Engineering
Peiqi Cui, Shaojie Wang, Haijia Su
Summary: Fe3O4 nanoparticles modified Aspergillus tubingensis mycelial pellets-based anaerobic granular sludge (Fe3O4@AT-AGS) was developed to improve the catalytic efficiency and stability of hydrogen-producing bacteria (HPB). The Fe3O4@AT-AGS protected flora and increased flora diversity and stability. The porous structure promoted the transfer from lactate-producing bacteria (LPB) to HPB. The Fe3O4@AT-AGS significantly enhanced the abundance, dehydrogenase activity, and stability of HPB.
BIORESOURCE TECHNOLOGY
(2022)
Article
Food Science & Technology
Wenyang Zhu, Bo Jiang, Fang Zhong, Jingjing Chen, Tao Zhang
Summary: This study investigated the effects of fermentation with Lactobacillus plantarum, Pediococcus pentosaceus, and Saccharomyces cerevisiae on reducing fishy odor in kelp. Results showed that Saccharomyces cerevisiae was the most effective in decreasing the volatile organic compounds associated with fishy notes, with a 91% decrease in unsaturated aldehydes. The reduction in fishy notes was related to the decrease in alpha,beta-unsaturated carbonyl groups.
Article
Agricultural Engineering
Yiming Yu, Guanghui Chen, Deshuang Yu, Yanling Qiu, Songjie Li, Enhui Guo
Summary: The process performance of partial denitrification of Enteromorpha was studied using a novel anaerobic fermentation integrated fixed-film activated sludge (IFAS-AFPD) system. The optimal reaction conditions were determined using the response surface method, and the experiment was conducted under these conditions. The results showed that the nitrogen removal effect was best at a salinity of 12.2 g/L, a Carbon-Nitrogen ratio of 4, a pH of 8.5, with Nitrite Accumulation Rate, Nitrate Removal Rate, and Chemical Oxygen Demand Utilization Rate reaching 77%, 89%, and 51% respectively. The microbial community analysis revealed that the Enteromorpha ferment liquid was more beneficial for the growth of Bacteroidetes compared to sodium acetate (CH3COONa).
BIORESOURCE TECHNOLOGY
(2023)
Article
Agricultural Engineering
Zhi-Peng Wang, Pei-Kang Wang, Yan Ma, Jia-Xue Lin, Cheng-Long Wang, Yu-Xiang Zhao, Xin-Yue Zhang, Bei-Chen Huang, Shou-Geng Zhao, Lei Gao, Jing Jiang, Hai-Ying Wang, Wei Chen
Summary: The study demonstrated that the addition of Laminaria japonica hydrolysate (LPH) is a feasible and efficient strategy to promote fucoxanthin accumulation. In the LPH group, both fucoxanthin content and biomass were significantly increased.
BIORESOURCE TECHNOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Xue-Ying Li, Yu-Jing Wang, Shun Chen, Li-Hua Pan, Qiang-Ming Li, Jian-Ping Luo, Xue-Qiang Zha
Summary: The present study demonstrated that LJP61A significantly reduced the lesion burden in atherosclerotic mice and alleviated lipid deposition in Ox-LDL-stimulated macrophages. Moreover, LJP61A enhanced autophagy-mediated macrophage polarization, leading to reduced inflammation and atherosclerosis.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Agricultural Engineering
Ranjna Sirohi, Jaemin Joun, Ji Young Lee, Byung Sun Yu, Sang Jun Sim
Summary: This review discusses the use of novel microalgal-bacterial consortium as a solution for the treatment and resource recovery of dairy, starch and aquaculture wastewater. Biofilm reactors containing anaerobic and aerobic sludge have shown high COD and nutrient removal efficiency in the treatment of dairy and starch processing wastewater. However, treatment of aquaculture processing wastewater requires a salt-tolerant bacteria-microalgae consortium.
BIORESOURCE TECHNOLOGY
(2022)
Editorial Material
Agricultural Engineering
Jo-Shu Chang, S. Venkata Mohan, Sang Jung Sim, Duu-Jong Lee, Maria Barbosa
BIORESOURCE TECHNOLOGY
(2022)
Article
Biophysics
Sojin Song, Jong Uk Lee, Myeong Jin Jeon, Soohyun Kim, Sang Jun Sim
Summary: An advanced plasmonic biosensor based on DNA-assembled nanoarchitecture has been developed for accurate detection of exosomal miRNAs in human serum, which can differentiate Alzheimer's disease patients from healthy controls by measuring the levels of exosomal miRNA-125b and miRNA-361.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biophysics
Woo Hyun Kim, Jong Uk Lee, Myeong Jin Jeon, Kyong Hwa Park, Sang Jun Sim
Summary: Urinary exosomal miRNAs have emerged as valuable biomarkers for early-stage diagnosis and prognosis of prostate cancer due to their non-invasiveness, stability, and representation of cell status. However, developing an accurate detection method for urinary exosomal miRNAs is challenging due to their low abundance and sequence homology. In this study, a label-free miRNA sensing platform using surface-enhanced Raman scattering (SERS) was developed, based on a three-dimensional hierarchical plasmonic nano-architecture, for the detection of urinary exosomal miRNAs. Clinical validation using urinary samples demonstrated that the SERS sensor achieved high diagnostic accuracy for distinguishing prostate cancer patients from healthy controls based on differential expression of urinary exosomal miRNAs. This study highlights the potential of the SERS sensor for facile and accurate measurement of miRNA expression and its importance in disease diagnosis.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Energy & Fuels
Ranjna Sirohi, Hong Il Choi, Sang Jun Sim
Summary: Microalgae have emerged as an excellent biological resource for biorefineries due to their ability to accumulate diverse CO2-derived bioproducts, such as fuels, chemical building blocks, and pharmaceuticals. Their biomass does not compete with food production and clean water, making the entire process highly sustainable.Various processes, including drying, chemical extraction, anaerobic digestion, and thermochemical treatments, can be used to obtain microalgal biomass-derived fuels for different end-uses.
Review
Plant Sciences
Sabeela Beevi Ummalyma, Ranjna Sirohi, Aswathy Udayan, Pooja Yadav, Abhay Raj, Sang Jun Sim, Ashok Pandey
Summary: Microalgae are cell factories that can be used to produce renewable energy, food, feed, pharmaceuticals, and nutraceuticals. The challenges of mass cultivation and biomass recovery limit the industrial application of microalgae. Cultivating microalgae in wastewater has been encouraged for sustainable bioeconomy. Wastewater from the food industry provides a less-toxic growth medium for low-cost microalgal biomass production. Microalgae are potential biocatalysts for wastewater bioremediation and offer a universal alternative for resource recovery from wastewater.
PHYTOCHEMISTRY REVIEWS
(2023)
Review
Green & Sustainable Science & Technology
Hong Il Choi, Young Joon Sung, Min Eui Hong, Jonghee Han, Byoung Koun Min, Sang Jun Sim
Summary: Microalgae is an efficient way to sequester carbon dioxide and produce marketable products. Using whole microalgal biomass as end-products offers a streamlined production process and has high potential for reducing energy and CO2 emissions. The limited commercial examples and established methods have hindered the practicality of this strategy, but recent applications have shown its feasibility and potential.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2022)
Article
Agricultural Engineering
Jaemin Joun, Ranjna Sirohi, Sang Jun Sim
Summary: This study compared the culture method using sodium acetate and glucose as organic carbon sources with autotrophy in Haematococcus pluvialis. In the 12-day culture, mixotrophy with sodium acetate and glucose increased biomass by 40.4% and 77.1% respectively compared to autotrophy, but the mechanisms were different. Mixotrophy with glucose increased biomass by directly supplying substrate and ATP to the TCA cycle while inhibiting photosynthesis. Gene expressions related to glycolysis and carbon fixation pathway were confirmed in autotrophy and mixotrophy with glucose and acetate. The proposed metabolism in mixotrophy with acetate and glucose was analyzed through autotrophic and heterotrophic metabolism.
BIORESOURCE TECHNOLOGY
(2023)
Article
Agricultural Engineering
Ha Eun Yang, Byung Sun Yu, Sang Jun Sim
Summary: The aim of this study was to increase the productivity of biomass with high astaxanthin content by developing a mutant strain of Haematococcus pluvialis with strong environmental tolerance. The mutant M5 strain, selected through gamma irradiation, showed improved biomass and astaxanthin production under high-salinity and high-light intensity conditions. M5 demonstrated an increase in biomass and astaxanthin productivity by 86.70% and 66.15% respectively, compared to untreated cells.
BIORESOURCE TECHNOLOGY
(2023)
Article
Agricultural Engineering
So Young Lee, Jeong Seop Lee, Sang Jun Sim
Summary: Wastewater treatment plants emit a large amount of greenhouse gases, but mixotrophic microalgae cultivation using wastewater has been proposed as a solution for CO2 mitigation and wastewater treatment. This study used waste soy sauce as a medium for Chlorella sorokiniana UTEX 2714 cultivation and found that using a 20% (v/v) 10-fold diluted soy sauce medium increased biomass and fatty acid methyl ester (FAME) productivity by 1.93 and 1.76 times, respectively. High biomass productivity was achieved under high-intensity light with a high soy sauce content, although it inhibited cell growth in photoautotrophic environments. Furthermore, the combination of industrial flue gas treatment with wastewater led to a 42% improvement in biomass production. These results suggest that mixotrophic microalgal cultivation has the potential to address climate change and water pollution while producing valuable products and contributing to a sustainable society.
BIORESOURCE TECHNOLOGY
(2023)
Article
Biophysics
Sojin Song, Jong Uk Lee, Myeong Jin Jeon, Soohyun Kim, Chan-Nyoung Lee, Sang Jun Sim
Summary: Alzheimer's disease is a neurodegenerative condition that is challenging to diagnose early due to the lack of robust biomarkers and limited access to neuroimaging and cerebrospinal fluid tests. Exosomes in body fluids are being explored as diagnostic biomarkers that reflect neuropathological features. A programmable curved plasmonic nanoarchitecture-based biosensor has been developed to accurately diagnose Alzheimer's disease.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Plant Sciences
Jaemin Joun, Ranjna Sirohi, Byung Sun Yu, Ha Eun Yang, Sang Jun Sim
Summary: Microalgae cultivation using wastewater is an effective method for wastewater treatment and carbon footprint reduction. Wastewater provides essential nutrients for microalgae growth, while greenhouse gas emissions can be mitigated through Carbon Capture, Utilization, and Storage technology. This review comprehensively discusses the application of microalgae in capturing carbon and treating wastewater, highlighting the potential for improving productivity, reducing costs, and promoting environmental sustainability.
PHYTOCHEMISTRY REVIEWS
(2023)
Article
Biotechnology & Applied Microbiology
Ranjna Sirohi, V. Vivekanand, Ashutosh Kumar Pandey, Ayon Tarafdar, Mukesh Kumar Awasthi, Amita Shakya, Sang Hyoun Kim, Sang Jun Sim, Hoang A. Tuan, Ashok Pandey
Summary: The transition from fossil fuels to non-conventional sources is necessary for addressing the global energy crisis and environmental issues. Organic waste from various industries can be utilized to produce gaseous fuels through different biochemical strategies. However, current biogas and biohydrogen production practices are inefficient and require interventions to improve biofuel yield. Adding biochar has been shown to enhance gaseous fuel production by adsorbing inhibitors and activating gas-producing microorganisms. This review explores the effect of biochar on gaseous biofuel production and highlights the need for a circular bioeconomy approach.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2023)
Article
Chemistry, Multidisciplinary
Sang Ki Kim, Jong Uk Lee, Myeong Jin Jeon, Soo-Kyung Kim, Sang-Hyun Hwang, Min Eui Hong, Sang Jun Sim
Summary: A colorimetric-fluorescent dual-mode lateral flow immunoassay sensor incorporating metal-enhanced fluorescence (MEF) was developed for the rapid and sensitive serological detection of SARS-CoV-2 IgG.
Article
Biotechnology & Applied Microbiology
Sukhyeong Cho, Yun Seo Lee, Hanyu Chai, Sang Eun Lim, Jeong Geol Na, Jinwon Lee
Summary: Ectoine production was significantly enhanced in M. alcaliphilum 20Z by disrupting the ectD and ectR genes under optimized conditions, leading to the highest ectoine production from methane to date. This study demonstrates effective genetic engineering in methanotrophic bacteria, with enhanced ectoine production from methane as the sole carbon source, suggesting a potential transformational path to commercial sugar-based ectoine production.
BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS
(2022)
