Impact of cultivation conditions onN-glycosylation of influenza virus a hemagglutinin produced in MDCK cell culture

Toward Animal Cell Culture-Based Influenza Vaccine Design: Viral Hemagglutinin N-Glycosylation Markedly Impacts Immunogenicity

(2012) J. Hutter et al.   JOURNAL OF IMMUNOLOGY

Glycan-Dependent Immunogenicity of Recombinant Soluble Trimeric Hemagglutinin

(2012) R. P. de Vries et al.   JOURNAL OF VIROLOGY

Safety of MDCK cell culture-based influenza vaccines

(2011) Jens-Peter Gregersen et al.   Future Microbiology

A new glycoengineered insect cell line with an inducibly mammalianized protein N-glycosylation pathway

(2011) Jared J Aumiller et al.   GLYCOBIOLOGY

Impact of Influenza Virus Adaptation Status on HAN-Glycosylation Patterns in Cell Culture-Based Vaccine Production

(2011) Jana Rödig et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

Impact of Host Cell Line Adaptation on Quasispecies Composition and Glycosylation of Influenza A Virus Hemagglutinin

(2011) Jana Verena Roedig et al.   PLoS One

MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivation

(2010) Yvonne Genzel et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

High-density microcarrier cell cultures for influenza virus production

(2010) A. Bock et al.   BIOTECHNOLOGY PROGRESS

High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state

(2010) C. Seitz et al.   JOURNAL OF GENERAL VIROLOGY

Optimized Workflow for Preparation of APTS-Labeled N-Glycans Allowing High-Throughput Analysis of Human Plasma Glycomes using 48-Channel Multiplexed CGE-LIF

(2010) L. Renee Ruhaak et al.   JOURNAL OF PROTEOME RESEARCH

Virus–host cell interactions in vaccine production cell lines infected with different human influenza A virus variants: A proteomic approach

(2010) Diana Vester et al.   Journal of Proteomics

Glycosylation at 158N of the Hemagglutinin Protein and Receptor Binding Specificity Synergistically Affect the Antigenicity and Immunogenicity of a Live Attenuated H5N1 A/Vietnam/1203/2004 Vaccine Virus in Ferrets

(2010) W. Wang et al.   JOURNAL OF VIROLOGY

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Differential activation of host cell signalling pathways through infection with two variants of influenza A/Puerto Rico/8/34 (H1N1) in MDCK cells

(2010) B. Heynisch et al.   VACCINE

A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor

(2010) V. Lohr et al.   VACCINE

The influenza A virus hemagglutinin glycosylation state affects receptor-binding specificity

(2010) Robert P. de Vries et al.   VIROLOGY

Identification of cell culture conditions to controlN-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells

(2009) Martin Gawlitzek et al.   BIOTECHNOLOGY AND BIOENGINEERING

Trivalent MDCK cell culture-derived influenza vaccine Optaflu®(Novartis Vaccines)

(2009) Alexander Doroshenko et al.   Expert Review of Vaccines

Continuous cell lines as a production system for influenza vaccines

(2009) Yvonne Genzel et al.   Expert Review of Vaccines

An HPLC-MALDI MS method for N-glycan analyses using smaller size samples: Application to monitor glycan modulation by medium conditions

(2009) Michael P. Gillmeister et al.   GLYCOCONJUGATE JOURNAL

Glycan analysis in cell culture-based influenza vaccine production: Influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin

(2009) Jana Schwarzer et al.   VACCINE

Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production—Flow cytometry and mathematical modeling

(2009) J. Schulze-Horsel et al.   VACCINE

New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: Studies on growth, metabolism and virus propagation

(2009) V. Lohr et al.   VACCINE

Pre-clinical development of cell culture (Vero)-derived H5N1 pandemic vaccines

(2008) M. Keith Howard et al.   BIOLOGICAL CHEMISTRY

The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells

(2008) Jong Hyun Nam et al.   BIOTECHNOLOGY AND BIOENGINEERING

N-glycan analysis by CGE-LIF: Profiling influenza A virus hemagglutininN-glycosylation during vaccine production

(2008) Jana Schwarzer et al.   ELECTROPHORESIS

High titer growth of human and avian influenza viruses in an immortalized chick embryo cell line without the need for exogenous proteases

(2008) Kristen A. Smith et al.   VACCINE

Monitoring influenza virus content in vaccine production: Precise assays for the quantitation of hemagglutination and neuraminidase activity

(2007) Bernd Kalbfuss et al.   BIOLOGICALS

Stabilizing the glycosylation pattern of influenza B hemagglutinin following adaptation to growth in eggs

(2007) Zhongying Chen et al.   VACCINE

Effect of Shear Stress on Intrinsic CHO Culture State and Glycosylation of Recombinant Tissue-Type Plasminogen Activator Protein

(2003) Ryan S. Senger et al.   BIOTECHNOLOGY PROGRESS