Production of miltiradiene by metabolically engineeredSaccharomyces cerevisiae

Modular Pathway Engineering of Diterpenoid Synthases and the Mevalonic Acid Pathway for Miltiradiene Production

(2012) Yongjin J. Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzymatic13C Labeling and Multidimensional NMR Analysis of Miltiradiene Synthesized by Bifunctional Diterpene Cyclase inSelaginella moellendorffii

(2011) Yoshinori Sugai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic engineering tanshinone biosynthetic pathway in Salvia miltiorrhiza hairy root cultures

(2011) Guoyin Kai et al.   METABOLIC ENGINEERING

Domain loss has independently occurred multiple times in plant terpene synthase evolution

(2011) Matthew L. Hillwig et al.   PLANT JOURNAL

Diversion of Flux toward Sesquiterpene Production inSaccharomyces cerevisiaeby Fusion of Host and Heterologous Enzymes

(2010) Line Albertsen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Enhanced Production of a Plant Monoterpene by Overexpression of the 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Catalytic Domain in Saccharomyces cerevisiae

(2010) J. Rico et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cloning and characterization of a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from Salvia miltiorrhiza involved in diterpenoid tanshinone accumulation

(2010) Zhubo Dai et al.   JOURNAL OF PLANT PHYSIOLOGY

Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control

(2010) E. Leonard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

(2010) P. K. Ajikumar et al.   SCIENCE

Overproduction of Geranylgeraniol by Metabolically Engineered Saccharomyces cerevisiae

(2009) K. Tokuhiro et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Functional Genomics Approach to Tanshinone Biosynthesis Provides Stereochemical Insights

(2009) Wei Gao et al.   ORGANIC LETTERS

Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production

(2008) Benedikt Engels et al.   METABOLIC ENGINEERING

Terpenoids: Opportunities for Biosynthesis of Natural Product Drugs Using Engineered Microorganisms

(2008) Parayil Kumaran Ajikumar et al.   MOLECULAR PHARMACEUTICS